Polymers & Resins Available — Bulk Only

Hexamethylene Diisocyanate (HDI)

HDI
CAS 822-06-0 · Formula C8H12N2O2 · MW 168.19 g/mol

The aliphatic diisocyanate behind weather- and UV-stable two-component polyurethane topcoats. It is mainly converted to higher-molecular-weight HDI-based polyisocyanates (biuret and isocyanurate) that act as crosslinkers in two-component polyurethane paint systems for automotive refinish, marine, and industrial-maintenance coatings.

Safety Data Sheet
UN Number
UN 2281
Hazard Class
Class 6.1
HS Code
2929.10
At a Glance
Material Family
Polymers & Resins
Record Type
Pure compound
Primary Role
Crosslinking / Curing · Synthesis Intermediate
Functional Roles
1,6-HEXAMETHYLENE DIISOCYANATE
NOT REPORTED
Applications & Use Cases
  • PU coatings: Crosslinker chemistry for light-stable two-component polyurethane paints.
  • Polyisocyanate hardeners: Feedstock for HDI biuret and isocyanurate curing agents.
  • Automotive refinish: Used in high-performance refinish and topcoat systems.
  • PU elastomers: Component of polyurethane elastomers.
Physical Properties
Physical Description
Hexamethylene diisocyanate appears as a colorless crystalline solid. Toxic by ingestion and is strongly irritating to skin and eyes. It is used to make nylon
Appearance
Clear, colorless to slightly yellow liquid
Odor
Sharp, pungent odor
Boiling Point
255 °C at 760 mmHg
Melting Point
-55 °C
Flash Point
140 °C
Solubility
Reacts with water
Density
1.0528 at 20 °C
Vapor Density
Relative vapor density (air = 1): 5.8
Vapor Pressure
0.05 mmHg at 24 °C
LogP
1.08
Autoignition Temperature
454 °C
Odor Threshold
The absolute perception limit is 0.001 ppm and 100% recognition at 0.02 ppm
Refractive Index
Index of refraction: 1.4585 at 20 °C/D
Safety & Handling
Full SDS available on request

A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.

DOT / UN Transport Classification
DOT hazard class 6.1 placard
UN / DOT NumberUN 2281
Hazard Class / DivisionClass 6.1
Packing GroupII
Proper Shipping NameHexamethylene diisocyanate

Transport classification per the UN Model Regulations / 49 CFR 172.101 Hazardous Materials Table. Confirm against the grade-specific SDS (Section 14) before shipping.

HS / Tariff Classification
Harmonized System (HS) Code — 6-digit international heading
2929 . 10
Chapter 29
Organic chemicals
Heading 29.29
Internationally harmonized (WCO HS)
Subheading 2929.10
6-digit international code — national tariff line adds further digits
Chemical Identity
CAS Number
822-06-0
Molecular Formula
C8H12N2O2
Molecular Weight
168.19 g/mol
IUPAC Name
1,6-diisocyanatohexane
INCI Name
1,6-HEXAMETHYLENE DIISOCYANATE
PubChem CID
InChI Key
RRAMGCGOFNQTLD-UHFFFAOYSA-N
Synonyms & Trade Names
1,6-Diisocyanatohexane HEXAMETHYLENE DIISOCYANATE 1,6-Hexamethylene diisocyanate Hexane, 1,6-diisocyanato- Hexane 1,6-diisocyanate 1,6-Hexylene diisocyanate Hexamethylene-1,6-diisocyanate hexamethylenediisocyanate Isocyanic acid, hexamethylene ester 1,6-Hexanediol diisocyanate TL 78 Szesciometylenodwuizocyjanian Metyleno-bis-fenyloizocyjanian 1,6-hexane diisocyanate Hexamethylendiisokyanat HMDI Desmodur H Isocyanic acid, diester with 1,6-hexanediol GMDI
Full Description

Hexamethylene diisocyanate (CAS 822-06-0) is an aliphatic diisocyanate used to make light-stable polyurethane coatings and elastomers. It is mainly converted to higher-molecular-weight HDI-based polyisocyanates (biuret and isocyanurate) that act as crosslinkers in two-component polyurethane paint systems for automotive refinish, marine, and industrial-maintenance coatings. Supplied as a bulk isocyanate intermediate.

Frequently Asked Questions

What is hexamethylene diisocyanate used for?

Hexamethylene diisocyanate (HDI, CAS 822-06-0) is an aliphatic diisocyanate used to make light-stable polyurethane coatings and elastomers. It is mainly converted to HDI-based polyisocyanate crosslinkers (biuret and isocyanurate) for two-component polyurethane paints in automotive refinish, marine, and industrial-maintenance systems. RawSource supplies it as a bulk isocyanate intermediate.

What is HDI biuret and isocyanurate (trimer)?

HDI is commonly reacted into higher-molecular-weight biuret and isocyanurate (trimer) polyisocyanates that serve as the hardener component in two-component polyurethane coatings, offering light stability and durability. RawSource supplies HDI as the upstream intermediate; specify whether you need monomer or a derivative on the RFQ.

What is the CAS number and HS code for hexamethylene diisocyanate?

HDI is CAS 822-06-0, molecular formula C8H12N2O2, classified under HS heading 2929.10 (isocyanates). Confirm destination-country tariff treatment with your broker and request the CoA and SDS for import and handling documentation.

How is hexamethylene diisocyanate shipped, given its UN number?

HDI is assigned UN 2281 (hexamethylene diisocyanate) and ships under DOT/IATA/IMDG hazardous-materials rules with the required packaging, labeling, and documentation. RawSource provides the SDS with each order; coordinate packaging and transport mode with your carrier.

How is bulk HDI packaged and quoted?

RawSource ships HDI as a bulk liquid intermediate in DOT-compliant drums and larger arrangements for coatings and elastomer manufacturers. Pricing depends on volume, packaging, and hazmat freight; submit an RFQ with your quantity and ship-to for a current quote with CoA and SDS.

Disclaimer. Information on this page — including properties, identifiers, hazard, transport (DOT/UN) and tariff (HS) classifications, and applications — is provided for general reference and is compiled from authoritative public sources (e.g. PubChem/ECHA, 49 CFR 172.101, the Harmonized Tariff Schedule). Values are typical and are not a guaranteed specification; the Certificate of Analysis (CoA) for the lot purchased governs. Products are sold for industrial and professional use only. Nothing here is a medical, health, or efficacy claim or advice. Always consult the current Safety Data Sheet (SDS) before handling, storage, transport or disposal, and confirm regulatory status, classification and suitability for your application and jurisdiction. Hazard, transport and tariff classifications must be verified for your specific shipment. RawSource makes no warranty, express or implied, and assumes no liability for use of this information. Trademarks. Third-party trademarks and brand names are the property of their respective owners; any reference is nominative — used only to identify a comparable product — and does not imply affiliation with, sponsorship by, or endorsement by the trademark owner.