Surfactants - Nonionic Available — Bulk Only

Polysorbate 40 (Polyoxyethylene 20 Sorbitan Monopalmitate)

CAS 9005-66-7 · Formula C26H50O10 · MW 522.7 g/mol

The palmitate polysorbate, a nonionic emulsifier bridging the laurate and stearate grades for oil-in-water systems. It serves as an emulsifier, surface-active agent, and stabilizer in food, cosmetic, and industrial formulations.

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HS Code
3402.42
At a Glance
Material Family
Surfactants - Nonionic
Record Type
Pure compound
Primary Role
Cleaning / Degreasing · Surfactancy
Functional Roles
POLYSORBATE 40
SURFACTANT - CLEANSINGSURFACTANT - EMULSIFYING
Applications & Use Cases
  • Emulsification: Oil-in-water nonionic emulsifier
  • Stabilizing: Stabilizes emulsions and dispersions
  • Wetting & dispersing: Surface-tension reduction and oil dispersion
Safety & Handling
Full SDS available on request

A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.

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HS / Tariff Classification
Harmonized System (HS) Code — 6-digit international heading
3402 . 42
Chapter 34
Soap, organic surface-active agents, washing and lubricating preparations, waxes
Heading 34.02
Internationally harmonized (WCO HS)
Subheading 3402.42
6-digit international code — national tariff line adds further digits
Chemical Identity
CAS Number
9005-66-7
Molecular Formula
C26H50O10
Molecular Weight
522.7 g/mol
IUPAC Name
2-[(2R)-2-[(2R,3R,4R)-3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl dodecanoate
INCI Name
POLYSORBATE 40
PubChem CID
InChI Key
HMFKFHLTUCJZJO-OQUNMALSSA-N
Synonyms & Trade Names
Polyoxyethylene (20) sorbitan monopalmitate Polysorbate 40 Tween 40 POLYSORBATE 40 FCC
Full Description

Polysorbate 40 (CAS 9005-66-7) is a nonionic surfactant of sorbitan, palmitic acid, and about twenty ethylene-oxide units. It serves as an emulsifier, surface-active agent, and stabilizer in food, cosmetic, and industrial formulations. Polysorbates are established emulsifiers and surfactants across these sectors.

Applications of Polysorbate 40

SectorUse
Food & beverageEmulsifier and stabilizer (food-additive designation E434) in bakery, dairy and emulsified foods.
Personal care & cosmeticsAn oil-in-water emulsifier and solubilizer for creams, lotions and oil-soluble actives.
Pharmaceutical & life scienceA nonionic excipient (solubilizer/emulsifier) for oral and topical formulations.
IndustrialEmulsifier, wetting agent and dispersant in coatings, textile and agrochemical systems.

HLB and grade selection

Polysorbate 40 has an HLB of ~15.6, so it is hydrophilic and water-soluble and builds oil-in-water (O/W) emulsions. To dial in a target emulsion HLB it is commonly paired with the lipophilic sorbitan ester (sorbitan monopalmitate, HLB ~6.7): the water-soluble polysorbate and the oil-soluble sorbitan ester together set the system HLB for a stable emulsion. Grades range from multicompendial pharmaceutical (NF / USP / EP) and food (FCC) to technical/industrial, with kosher and halal certification available; match the grade and compendial status to your application and jurisdiction.

Frequently Asked Questions

What is polysorbate 40, and what is it derived from?

Polysorbate 40 (CAS 9005-66-7) is a nonionic surfactant built from sorbitan, palmitic acid, and about twenty ethylene-oxide units. The palmitic-acid component is the fatty-acid portion that distinguishes it from other polysorbate grades.

What is polysorbate 40 used for?

It serves as an oil-in-water nonionic emulsifier, a stabilizer for emulsions and dispersions, and a wetting and dispersing agent. It is applied across food, cosmetic, and industrial formulations.

What is the difference between polysorbate 40 and polysorbate 20 or 60?

The grades differ by their fatty-acid chain: polysorbate 20 uses lauric acid, 40 uses palmitic acid, and 60 uses stearic acid, all with about twenty ethylene-oxide units. Choose the grade by the fatty-acid chain length and emulsion behavior your formulation needs.

Is an NF grade of polysorbate 40 available, and what documentation comes with it?

This material is offered as NF grade. Request the NF grade documentation with your order, along with the batch CoA and SDS.

What is the HS code and bulk packaging for polysorbate 40?

It classifies under HS 3402.42 (non-ionic organic surface-active agents) and typically ships in drums, totes, or IBCs. Send your target volume and packaging for a bulk quote, and we will confirm availability.

Disclaimer. Information on this page — including properties, identifiers, hazard, transport (DOT/UN) and tariff (HS) classifications, and applications — is provided for general reference and is compiled from authoritative public sources (e.g. PubChem/ECHA, 49 CFR 172.101, the Harmonized Tariff Schedule). Values are typical and are not a guaranteed specification; the Certificate of Analysis (CoA) for the lot purchased governs. Products are sold for industrial and professional use only. Nothing here is a medical, health, or efficacy claim or advice. Always consult the current Safety Data Sheet (SDS) before handling, storage, transport or disposal, and confirm regulatory status, classification and suitability for your application and jurisdiction. Hazard, transport and tariff classifications must be verified for your specific shipment. RawSource makes no warranty, express or implied, and assumes no liability for use of this information. Trademarks. Third-party trademarks and brand names are the property of their respective owners; any reference is nominative — used only to identify a comparable product — and does not imply affiliation with, sponsorship by, or endorsement by the trademark owner.