Silicone Fluids & Oils Available — Bulk Only

Simethicone (Simeticone, Activated Dimethicone)

CAS 8050-81-5

Silica-activated polydimethylsiloxane built for foam control in demanding process streams. It functions as an antifoaming and defoaming agent, used to control foam in pharmaceutical and chemical manufacturing processes, as a food-grade antifoaming and anticaking additive (JECFA), and as an antifoaming ingredient in cosmetics.

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CAS Number
8050-81-5
Material Family
Silicone Fluids & Oils
At a Glance
Material Family
Silicone Fluids & Oils
Record Type
COMPOUND
Primary Role
Defoaming / Foam Control
Functional Roles
Simethicone
Industries Served
Applications & Use Cases
  • Process antifoam: Controls foam in pharmaceutical and chemical manufacturing processes.
  • Food additive: JECFA-classified antifoaming and anticaking agent for food processing.
  • Cosmetic antifoam: Antifoaming ingredient in cosmetic and personal-care formulations.
  • Defoamer: Silica-activated silicone for rapid foam knockdown in aqueous and non-aqueous systems.
Physical Properties
Active polydimethylsiloxane
90.5-99.0%
Silicon dioxide
4.0-7.0%
Form
Compound or aqueous emulsion
Safety & Handling
Full SDS available on request

A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.

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Chemical Identity
CAS Number
8050-81-5
INCI Name
Simethicone
Full Description

Simethicone (CAS 8050-81-5) is polydimethylsiloxane, a polymer of roughly 200-350 dimethylsiloxane units, blended with finely divided silica. It functions as an antifoaming and defoaming agent, used to control foam in pharmaceutical and chemical manufacturing processes, as a food-grade antifoaming and anticaking additive (JECFA), and as an antifoaming ingredient in cosmetics.

Frequently Asked Questions

What does simethicone do?

Simethicone (CAS 8050-81-5) is polydimethylsiloxane blended with finely divided silica that functions as an antifoaming and defoaming agent. The silica-activated silicone destabilizes foam for rapid foam knockdown in aqueous and non-aqueous systems.

What is simethicone used for industrially?

It controls foam in pharmaceutical and chemical manufacturing processes, serves as a JECFA-classified antifoaming and anticaking food additive, and acts as an antifoaming ingredient in cosmetic and personal-care formulations. It is supplied as a process defoamer raw material.

What is simethicone made from?

It is a silicone defoamer composed of polydimethylsiloxane (a polymer of roughly 200-350 dimethylsiloxane units) combined with finely divided silica. The silica activates the silicone fluid for faster foam collapse.

Is simethicone water soluble?

No. The polydimethylsiloxane base is hydrophobic and not water soluble; simethicone is typically used as an emulsion or dispersion to deliver the silicone into aqueous foaming systems. Confirm the delivery form on the product technical data.

How is simethicone supplied and quoted in bulk?

It is available in bulk packaging such as drums and totes for process and formulation use. Pricing is volume- and market-dependent; request a quote with your grade and target quantity. A CoA and SDS accompany each shipment.

Disclaimer. Information on this page — including properties, identifiers, hazard, transport (DOT/UN) and tariff (HS) classifications, and applications — is provided for general reference and is compiled from authoritative public sources (e.g. PubChem/ECHA, 49 CFR 172.101, the Harmonized Tariff Schedule). Values are typical and are not a guaranteed specification; the Certificate of Analysis (CoA) for the lot purchased governs. Products are sold for industrial and professional use only. Nothing here is a medical, health, or efficacy claim or advice. Always consult the current Safety Data Sheet (SDS) before handling, storage, transport or disposal, and confirm regulatory status, classification and suitability for your application and jurisdiction. Hazard, transport and tariff classifications must be verified for your specific shipment. RawSource makes no warranty, express or implied, and assumes no liability for use of this information. Trademarks. Third-party trademarks and brand names are the property of their respective owners; any reference is nominative — used only to identify a comparable product — and does not imply affiliation with, sponsorship by, or endorsement by the trademark owner.