Amines & Amides Available — Bulk Only

L-Leucine (Leucine)

CAS 61-90-5 · Formula C6H13NO2 · MW 131.17 g/mol

A branched-chain essential amino acid recognized as a low-concern processing aid and nutrition ingredient. It is used as a nutritional supplement and food flavoring/processing aid, as a substrate for biochemical research, and as a skin- and hair-conditioning ingredient in cosmetics.

Part of Amines & Amides
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HS Code
2922.49
At a Glance
Material Family
Amines & Amides
Record Type
Pure compound
Primary Role
Conditioning · Synthesis Intermediate
Functional Roles
LEUCINE
ANTISTATICHAIR CONDITIONINGSKIN CONDITIONING
Industries Served
Applications & Use Cases
  • Nutritional supplement: Branched-chain amino-acid ingredient for supplements and foods.
  • Processing aid: Food processing aid/additive (EPA Safer Chemical listed).
  • Flavoring agent: Food flavoring ingredient.
  • Cosmetic ingredient: Skin- and hair-conditioning agent.
Physical Properties
Melting Point
293 °C
Boiling Point
Sublimes at 145-148 °C. Decomposes at 293-295 °C (rapid heating, sealed tube)
Density
1.293 g/cu cm at 18 °C
Solubility
21500 mg/L (at 25 °C)
Vapor Pressure
0.00000001
Safety & Handling
Full SDS available on request

A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.

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HS / Tariff Classification
Harmonized System (HS) Code — 6-digit international heading
2922 . 49
Chapter 29
Organic chemicals
Heading 29.22
Internationally harmonized (WCO HS)
Subheading 2922.49
6-digit international code — national tariff line adds further digits
Chemical Identity
CAS Number
61-90-5
Molecular Formula
C6H13NO2
Molecular Weight
131.17 g/mol
IUPAC Name
(2S)-2-amino-4-methylpentanoic acid
INCI Name
LEUCINE
PubChem CID
InChI Key
ROHFNLRQFUQHCH-YFKPBYRVSA-N
Synonyms & Trade Names
L-leucine leucine (S)-Leucine (S)-2-Amino-4-methylpentanoic acid (2S)-2-amino-4-methylpentanoic acid Leucin (S)-2-Amino-4-methylvaleric acid (S)-(+)-Leucine L-alpha-Aminoisocaproic acid LEUCINE, L- Leucinum Leucina FEMA No. 3297 (2S)-alpha-leucine L-leucin L-(-)-2-Amino-4-methylpentanoic acid alpha-Aminoisocaproic acid L-Leuzin 2-amino-4-methylvaleric acid
Full Description

L-Leucine (CAS 61-90-5) is an essential branched-chain alpha-amino acid (C6H13NO2). It is used as a nutritional supplement and food flavoring/processing aid, as a substrate for biochemical research, and as a skin- and hair-conditioning ingredient in cosmetics.

Frequently Asked Questions

What is L-Leucine used for?

L-Leucine (CAS 61-90-5) is an essential branched-chain alpha-amino acid (C6H13NO2). It is used as an amino-acid ingredient in supplements and foods, as a food processing aid and flavoring ingredient, as a biochemical research substrate, and as a skin- and hair-conditioning ingredient in cosmetics.

Is L-Leucine a branched-chain amino acid (BCAA)?

Yes. Leucine is one of the three BCAAs, alongside isoleucine and valine, and is a primary input for BCAA blends and amino-acid formulations.

Is L-Leucine water soluble?

L-leucine has limited but real solubility in water; it is more readily soluble in dilute acid or base. Solubility behavior should be confirmed against your formulation system using lot-specific specifications.

What is the CAS number, formula, and HS code?

CAS 61-90-5, formula C6H13NO2, HS 2922.49 (amino-acids and their salts, other). Supplied to USP specification; lot-specific Certificate of Analysis and SDS are available on request.

What bulk packaging and order quantities are available?

It is distributed as a USP-grade ingredient in bulk packaging for manufacturing. Submit your target volume and USP/CoA documentation needs through a bulk RFQ for current pricing, pack sizes, and lead time.

Disclaimer. Information on this page — including properties, identifiers, hazard, transport (DOT/UN) and tariff (HS) classifications, and applications — is provided for general reference and is compiled from authoritative public sources (e.g. PubChem/ECHA, 49 CFR 172.101, the Harmonized Tariff Schedule). Values are typical and are not a guaranteed specification; the Certificate of Analysis (CoA) for the lot purchased governs. Products are sold for industrial and professional use only. Nothing here is a medical, health, or efficacy claim or advice. Always consult the current Safety Data Sheet (SDS) before handling, storage, transport or disposal, and confirm regulatory status, classification and suitability for your application and jurisdiction. Hazard, transport and tariff classifications must be verified for your specific shipment. RawSource makes no warranty, express or implied, and assumes no liability for use of this information. Trademarks. Third-party trademarks and brand names are the property of their respective owners; any reference is nominative — used only to identify a comparable product — and does not imply affiliation with, sponsorship by, or endorsement by the trademark owner.