LEUCINE- ▸ Nutritional supplement: Branched-chain amino-acid ingredient for supplements and foods.
- ▸ Processing aid: Food processing aid/additive (EPA Safer Chemical listed).
- ▸ Flavoring agent: Food flavoring ingredient.
- ▸ Cosmetic ingredient: Skin- and hair-conditioning agent.
A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.
Request SDS →L-Leucine (CAS 61-90-5) is an essential branched-chain alpha-amino acid (C6H13NO2). It is used as a nutritional supplement and food flavoring/processing aid, as a substrate for biochemical research, and as a skin- and hair-conditioning ingredient in cosmetics.
Regulatory & registration requirements
- TSCA (US):
- REACH (EU):
- EC number: 200-522-0
Source: EPA TSCA Inventory (July 2025 release) · ECHA CHEM — retrieved 2026-07-12
Frequently Asked Questions
What is L-Leucine used for?
L-Leucine (CAS 61-90-5) is an essential branched-chain alpha-amino acid (C6H13NO2). It is used as an amino-acid ingredient in supplements and foods, as a food processing aid and flavoring ingredient, as a biochemical research substrate, and as a skin- and hair-conditioning ingredient in cosmetics.
Is L-Leucine a branched-chain amino acid (BCAA)?
Yes. Leucine is one of the three BCAAs, alongside isoleucine and valine, and is a primary input for BCAA blends and amino-acid formulations.
Is L-Leucine water soluble?
L-leucine has limited but real solubility in water; it is more readily soluble in dilute acid or base. Solubility behavior should be confirmed against your formulation system using lot-specific specifications.
What is the CAS number, formula, and HS code?
CAS 61-90-5, formula C6H13NO2, HS 2922.49 (amino-acids and their salts, other). Supplied to USP specification; lot-specific Certificate of Analysis and SDS are available on request.
What bulk packaging and order quantities are available?
It is distributed as a USP-grade ingredient in bulk packaging for manufacturing. Submit your target volume and USP/CoA documentation needs through a bulk RFQ for current pricing, pack sizes, and lead time.
What is the REACH and TSCA regulatory status of L-Leucine (Leucine)?
L-Leucine (Leucine) (CAS 61-90-5) is subject to U.S. TSCA Inventory requirements; supplying it into the EU requires valid REACH registration ((EC) No 1907/2006). RawSource cannot verify a third-party supplier's registrations — buyers should require documented TSCA and REACH compliance for their jurisdiction and volume (EC 200-522-0).