- ▸ MDI precursor: Feedstock for methylene diphenyl diisocyanate and polymeric MDI.
- ▸ Epoxy curing agent: Hardener for epoxy resins.
- ▸ Polyurethane elastomers: Curing agent/chain extender for cast PU elastomers.
- ▸ High-performance polymers: Monomer for polyamide and polyimide resins.
A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.
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Transport classification per the UN Model Regulations / 49 CFR 172.101 Hazardous Materials Table. Confirm against the grade-specific SDS (Section 14) before shipping.
⚠ WARNING: This product can expose you to Diaminodiphenylmethane, which is known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.
Diaminodiphenylmethane (CAS 101-77-9), also called 4,4'-methylenedianiline, is an aromatic diamine used mainly as the precursor to methylene diphenyl diisocyanate (MDI) and polymeric MDI. PubChem also records its use as an epoxy and polyurethane-elastomer curing agent and as a monomer for polyamide and polyimide resins. Supplied as a bulk amine intermediate.
Regulatory & registration requirements
- TSCA (US):
- REACH (EU):
- EC number: 202-974-4
Source: EPA TSCA Inventory (July 2025 release) · ECHA CHEM — retrieved 2026-07-12
Restricted substance — regulatory status
Diaminodiphenylmethane (MDA, 4,4′-Methylenedianiline) (CAS 101-77-9) appears on the regulatory list(s) below. This is public regulatory information about the substance — not a statement about any specific supplier’s material, and not a safety claim. Confirm the current status for your jurisdiction and intended use.
- California Proposition 65: listed for cancer, listed 1 Jan 1988. A California Proposition 65 warning applies (see the warning above).
- REACH Authorisation List (Annex XIV): use or placing on the EU market after the sunset date (sunset 21 Aug 2014) requires a specific REACH authorisation. Sale and use outside the EU are not restricted by Annex XIV.
- REACH SVHC Candidate List (EU): listed 28 Oct 2008 on the basis of carcinogenic (Art. 57(a)). SVHC status triggers EU supplier-communication and notification duties above 0.1% w/w; it is not, by itself, a ban on sale.
Sources: ECHA Candidate List / Annex XIV / Annex XVII (echa.europa.eu); U.S. EPA TSCA; UN Stockholm Convention / EU POPs Regulation; California OEHHA Proposition 65 list. Retrieved 2026-07-13.
Frequently Asked Questions
What is diaminodiphenylmethane used for?
Diaminodiphenylmethane (MDA, CAS 101-77-9), also called 4,4'-methylenedianiline, is used mainly as the precursor to methylene diphenyl diisocyanate (MDI) and polymeric MDI. It also serves as an epoxy and polyurethane-elastomer curing agent and as a monomer for polyamide and polyimide resins.
What is methylenedianiline used for?
4,4'-Methylenedianiline is the same compound as MDA. Beyond being the feedstock for MDI/polymeric MDI, it is used as a hardener for epoxy resins, as a curing agent and chain extender for cast polyurethane elastomers, and as a monomer for high-performance polyamide and polyimide resins.
Is diaminodiphenylmethane the same as 4,4'-methylenedianiline?
Yes. Diaminodiphenylmethane (MDA) and 4,4'-methylenedianiline are names for the same aromatic diamine, CAS 101-77-9, formula C13H14N2. Specify by CAS when ordering to avoid synonym confusion.
How is MDA shipped and classified for transport?
For transport it is associated with UN 2651 (4,4'-diaminodiphenylmethane) and HS code 2921.59 (aromatic polyamines and derivatives: other). Consult the SDS for the full transport, GHS, and handling profile before arranging freight.
What is the cost of bulk MDA?
Bulk pricing depends on volume, packaging, and destination. Send your required quantity and ship-to details for a current quote; each shipment ships with a CoA and SDS.
What is the REACH and TSCA regulatory status of Diaminodiphenylmethane (MDA, 4,4'-Methylenedianiline)?
Diaminodiphenylmethane (MDA, 4,4'-Methylenedianiline) (CAS 101-77-9) is subject to U.S. TSCA Inventory requirements; supplying it into the EU requires valid REACH registration ((EC) No 1907/2006). RawSource cannot verify a third-party supplier's registrations — buyers should require documented TSCA and REACH compliance for their jurisdiction and volume (EC 202-974-4).