Request Quote
Amines & Amides Available — Bulk Only

L-Histidine Hydrochloride (L-Histidine HCl)

CAS 5934-29-2 · Formula C6H12ClN3O3 · MW 209.63 g/mol

The soluble hydrochloride salt of histidine, supplied for nutrition and culture-media manufacturing. It is used as a nutritional supplement and food ingredient, as a component of amino-acid and cell-culture media, and as a substrate for biochemical research.

Part of Amines & Amides
Request SDS
HS Code
2933.29
At a Glance
Material Family
Amines & Amides
Record Type
Pure compound
Primary Role
Conditioning · pH Adjustment
Functional Roles
Conditioning pH Adjustment Chelation / Sequestration Synthesis Intermediate
INCI Name
HISTIDINE HCL
CosIng Functions
HAIR CONDITIONINGSKIN CONDITIONING
Industries Served
Food & Beverage
Applications & Use Cases
  • ▸ Nutritional supplement: Soluble amino-acid ingredient for supplements and foods.
  • ▸ Culture & amino-acid media: Component of cell-culture and parenteral amino-acid media.
  • ▸ Research substrate: Reagent for biochemical research.
Safety & Handling
Full SDS available on request

A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.

Request SDS →
HS / Tariff Classification
Harmonized System (HS) Code — 6-digit international heading
2933 . 29
Chapter 29
Organic chemicals
Heading 29.33
Internationally harmonized (WCO HS)
Subheading 2933.29
6-digit international code — national tariff line adds further digits
Chemical Identity
CAS Number
5934-29-2
Molecular Formula
C6H12ClN3O3
Molecular Weight
209.63 g/mol
IUPAC Name
(2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid;hydrate;hydrochloride
INCI Name
HISTIDINE HCL
PubChem CID
165377
InChI Key
CMXXUDSWGMGYLZ-XRIGFGBMSA-N
Synonyms & Trade Names
L-Histidine Hydrochloride Monohydrate L-Histidine hydrochloride hydrate L-Histidine monohydrochloride monohydrate L-Histidine, monohydrochloride, monohydrate L-Histidine HCl hydrate Histidine monohydrochloride monohydrate Histidine hydrochloride hydrate histidine hydrochloride monohydrate Histidine, monohydrochloride, monohydrate, L- L-Histidine hydrochloride hydrate (JP17) HISTIDINE, L-, HYDROCHLORIDE MONOHYDRATE HISTIDINE, L-, MONOHYDROCHLORIDE MONOHYDRATE HISTIDINE MONOHYDROCHLORIDE MONOHYDRATE, (-)- L-HISTIDINE, HYDROCHLORIDE, HYDRATE (1:1:1) HISTIDINE HYDROCHLORIDE MONOHYDRATE [EP MONOGRAPH] L-HISTIDINE MONOHYDROCHLORIDE MONOHYDRATE [USP-RS]
Full Description

L-Histidine Hydrochloride (CAS 5934-29-2) is the hydrochloride (monohydrate) salt of the imidazole-bearing essential amino acid L-histidine (C6H12ClN3O3). It is used as a nutritional supplement and food ingredient, as a component of amino-acid and cell-culture media, and as a substrate for biochemical research.

Frequently Asked Questions

What is L-Histidine HCl used for?

L-Histidine Hydrochloride (CAS 5934-29-2) is the hydrochloride salt of the imidazole-bearing essential amino acid L-histidine. Industrially it is used as a soluble amino-acid ingredient in supplements and foods, as a component of cell-culture and parenteral amino-acid media, and as a biochemical research substrate.

What is the difference between L-histidine and L-histidine HCl?

L-histidine HCl is the hydrochloride (commonly monohydrate) salt of the free amino acid L-histidine. The salt form offers greater water solubility and handling stability, which is why it is specified for media and soluble formulation work.

Is L-Histidine HCl water soluble?

Yes. The hydrochloride salt is the water-soluble form of L-histidine, making it suitable for aqueous amino-acid and culture-media preparations.

What is the CAS number, molecular formula, and HS code?

CAS 5934-29-2, formula C6H12ClN3O3, HS 2933.29 (compounds containing an unfused imidazole ring, other). Supplied to FCC specification; lot-specific CoA and SDS are available on request.

What bulk packaging and order quantities are available?

It is distributed as an FCC-grade ingredient in bulk packaging for manufacturing. Submit your target volume and documentation requirements through a bulk RFQ for current pricing, pack sizes, and lead time.

Related Products
Dicyandiamide
CAS 461-58-5 · C2H4N4
Amines & Amides
Sodium Polyglutamate (Sodium PGA)
CAS 25513-46-6 · C5H8NNaO4
Amines & Amides
Trimethylhexamethylenediamine (TMD)
CAS 25513-64-8
Amines & Amides
1,2-Dimethylimidazole (1,2-DMI)
CAS 1739-84-0 · C5H8N2
Amines & Amides
Disclaimer. Information on this page — including properties, identifiers, hazard, transport (DOT/UN) and tariff (HS) classifications, and applications — is provided for general reference and is compiled from authoritative public sources (e.g. PubChem/ECHA, 49 CFR 172.101, the Harmonized Tariff Schedule). Values are typical and are not a guaranteed specification; the Certificate of Analysis (CoA) for the lot purchased governs. Products are sold for industrial and professional use only. Nothing here is a medical, health, or efficacy claim or advice. Always consult the current Safety Data Sheet (SDS) before handling, storage, transport or disposal, and confirm regulatory status, classification and suitability for your application and jurisdiction. Hazard, transport and tariff classifications must be verified for your specific shipment. RawSource makes no warranty, express or implied, and assumes no liability for use of this information. Trademarks. Third-party trademarks and brand names are the property of their respective owners; any reference is nominative — used only to identify a comparable product — and does not imply affiliation with, sponsorship by, or endorsement by the trademark owner.
Bulk & Specialty Sourcing

Ready to Source L-Histidine Hydrochloride (L-Histidine HCl)?

Our procurement team handles specification confirmation, lead time, and logistics.

Request a Quote Browse the Catalog