Polysorbate 80 NF, FCC

Chemical Formula:

C₆₄H₁₂₄O₂₆ (approximate, varies with polymerization)

CAS Number:

9005-65-6

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Polysorbate 80 NF, FCC

Chemical Formula:

C₆₄H₁₂₄O₂₆ (approximate, varies with polymerization)

CAS Number:

9005-65-6

Polysorbate 80 is a nonionic surfactant and emulsifier synthesized from sorbitol, ethylene oxide, and oleic acid. It is widely used to stabilize oil-in-water emulsions in pharmaceuticals, foods, and cosmetics. The NF grade ensures pharmaceutical quality standards, while the FCC designation confirms food-grade compliance. Its versatility makes it an essential excipient, stabilizer, and dispersing agent across multiple industries.

Characteristics

Molar Weight

~1310 g/mol

Melting Point

–5 °C

Boiling Point

Decomposes before boiling (> 100 °C)

Solubility

Freely soluble in water, ethanol, methanol

Density

~1.06 g/cm³

Forms

Viscous amber to yellow liquid

Odor

Mild, characteristic odor

USES AND APPLICATIONS

Key applications

Stabilizes emulsions in vaccines and injectables.
Solubilizes hydrophobic drugs in formulations.
Improves consistency in food emulsions.
Acts as dispersing agent in lotions and creams.
Supports controlled release in drug delivery.

Industries

Pharmaceuticals
Food & Beverages
Cosmetics & Personal Care
Biotechnology
Veterinary Formulations

Synonyms

Tween 80, polyoxyethylene sorbitan monooleate, sorbitan monooleate polyethoxylated

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