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D-Mannitol (Pearlitol SD200)

D-Mannitol (Pearlitol SD200)

Chemical Formula:

C₆H₁₄O₆

CAS Number:

69-65-8

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D-Mannitol (Pearlitol SD200)

Chemical Formula:

C₆H₁₄O₆

CAS Number:

69-65-8

D-Mannitol, marketed as Pearlitol SD200, is a naturally occurring sugar alcohol widely used as a pharmaceutical excipient, food additive, and nutraceutical ingredient. It is known for its cooling effect, low hygroscopicity, and excellent compressibility, making it ideal for direct compression in tablet formulations. With its USP/FCC grade, D-Mannitol is safe for oral and parenteral applications. It also serves as a bulking agent, sweetener, and stabilizer in foods, chewing gums, and medical formulations.

Characteristics

Molar Weight

182.17 g/mol

Melting Point

166–168 °C

Solubility

Freely soluble in water, slightly soluble in alcohol, insoluble in ether

Density

~1.52 g/cm³

Forms

White crystalline powder or granules

Odor

Odorless, slightly sweet taste

USES AND APPLICATIONS

Key applications

  • Used as a pharmaceutical excipient in tablets and capsules.
  • Acts as a bulking agent and stabilizer in nutraceuticals.
  • Serves as a low-calorie sweetener in food and chewing gum.
  • Applied in medical formulations as an osmotic diuretic.
  • Improves flowability and compressibility in solid dosage forms.

Industries

  • Pharmaceuticals
  • Nutraceuticals
  • Food & Beverages
  • Cosmetics & Personal Care
  • Medical & Clinical Applications

Synonyms

Mannitol, D-Mannitol, Mannite, E421

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