- ▸ Liquid aliphatic diisocyanate used to build light-stable polyurethane prepolymers and coatings
- ▸ Crosslinks hydroxyl resins in weatherable 2K-PU coatings, elastomers and adhesives
- ▸ Provides low color and good UV stability versus aromatic diisocyanates
A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.
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Trimethylhexamethylene diisocyanate (TMDI) is a branched aliphatic diisocyanate (2,2,4-/2,4,4-isomer mixture) used as a light-stable building block and crosslinker for high-performance, flexible, non-yellowing polyurethanes. Identity: CAS 32052-51-0.
What it is
TMDI (CAS 32052-51-0) is a liquid branched aliphatic diisocyanate. The methyl branches give low viscosity, liquid handling and flexibility, and it is fully aliphatic (light-stable).
How it works
Its two NCO groups react with polyols/amines to build polyurethane/polyurea; being aliphatic and branched it gives non-yellowing, flexible, low-viscosity systems and is also a building block for specialty polyisocyanates.
Applications
TMDI is used in light-stable polyurethane coatings, elastomers and adhesives and as a building block. It derives from TMD.
Forms, grades and handling
TMDI is supplied as a clear liquid in drums and bulk. Properties are typical reference values; the Certificate of Analysis (CoA) for the lot you buy governs. Isocyanates are moisture-sensitive and require respiratory/skin precautions; handle per the current Safety Data Sheet (SDS). Each lot ships with CoA, TDS and SDS.
Bulk supply and RFQ
RawSource sources Trimethylhexamethylene Diisocyanate direct from producers in bulk, with CoA, TDS and SDS per lot. Tell us your binder system, cure schedule and the performance you need, and we will quote the right grade. See the polyurethane catalysts guide for the catalysts that drive these reactions.
Typical Properties
Typical reference values, not a specification; the Certificate of Analysis (CoA) for the lot governs.
| Property | Typical Value |
|---|---|
| Chemical / class | Aliphatic diisocyanate (TMDI) |
| Function | Light-stable PU building block |
| CAS Number | 32052-51-0 |
| Molecular Formula | C11H18N2O2 |
| Molecular Weight | 210.27 g/mol |
| Handling | Refer to the current SDS |
Regulatory & registration requirements
- TSCA (US): Not found on the public (non-confidential) TSCA Inventory
- REACH (EU):
- EC number: 915-277-1
Source: EPA TSCA Inventory (July 2025 release) · ECHA CHEM — retrieved 2026-07-12
Frequently Asked Questions
What is trimethylhexamethylene diisocyanate (TMDI) used for?
TMDI (CAS 32052-51-0) is a branched aliphatic diisocyanate used as a light-stable, flexible, low-viscosity building block and crosslinker for high-performance polyurethane coatings, elastomers and adhesives.
How is bulk TMDI supplied and quoted?
RawSource supplies TMDI in bulk with CoA, TDS and SDS per lot. Pricing is quote-based on grade and volume; submit an RFQ with your binder system and cure schedule.
What is the REACH and TSCA regulatory status of Trimethylhexamethylene Diisocyanate (2,2,4-/2,4,4- isomer mixture)?
Trimethylhexamethylene Diisocyanate (2,2,4-/2,4,4- isomer mixture) (CAS 32052-51-0) is recorded as REACH-registered in ECHA's public CHEM database (EC 915-277-1); it was not found on EPA's public (non-confidential) TSCA Inventory file.