Amines & Amides Available — Bulk Only

N,N,N’,N’-Tetrakis(2-Hydroxyethyl)adipamide

HAA
CAS 6334-25-4 · Formula C14H28N2O6 · MW 320.38 g/mol

A crystalline beta-hydroxyalkylamide crosslinker for TGIC-free polyester powder coatings, curing via hydroxyl-carboxyl reaction for exterior-durable finishes.

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CAS Number
6334-25-4
Formula
C14H28N2O6
Molecular Weight
320.38 g/mol
Material Family
Amines & Amides
At a Glance
Material Family
Amines & Amides
Record Type
Compound
Primary Role
Crosslinking / Curing · Synthesis Intermediate
Applications & Use Cases
  • Serves as the primary crosslinker (hardener) for carboxyl-functional polyester resins in TGIC-free powder coatings, reacting with terminal -COOH groups to form ester linkages during the cure schedule.
  • Enables formulation of exterior-durable, weather-resistant powder coatings for architectural aluminum, fencing, and outdoor furniture where regulatory restrictions on TGIC apply.
  • Used at typical loadings around 5 percent of binder to deliver high-gloss, chemically resistant finishes with good mechanical flexibility and overbake stability.
  • Functions as a polyfunctional hydroxyl building block and synthesis intermediate for crosslinked polyester and polyurethane networks.
  • Supports low-VOC coil and general industrial powder coating lines seeking a non-isocyanate, non-TGIC curing chemistry.
Physical Properties
Appearance
white crystalline powder
Melting Point
120-125 C
Hydroxyl Value
approx. 630-700 mg KOH/g
Molecular Weight
320.38 g/mol
Functionality
4 (tetrafunctional hydroxyl)
Safety & Handling
Full SDS available on request

A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.

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Chemical Identity
CAS Number
6334-25-4
Molecular Formula
C14H28N2O6
Molecular Weight
320.38 g/mol
IUPAC Name
N,N,N',N'-tetrakis(2-hydroxyethyl)hexanediamide
PubChem CID
InChI Key
OKRNLSUTBJUVKA-UHFFFAOYSA-N
Synonyms & Trade Names
N,N,N',N'-Tetrakis(2-hydroxyethyl)hexanediamide Beta-hydroxyalkylamide Bis[N,N-di(2-hydroxyethyl)] adipamide Hexanediamide, N,N,N',N'-tetrakis(2-hydroxyethyl)- Comparable to Primid XL-552
Full Description

Tetrakis(2-hydroxyethyl)adipamide is the TGIC-free crosslinker for polyester powder coatings — a beta-hydroxyalkylamide (HAA, Primid-type) that cures carboxyl polyesters without TGIC. Identity: CAS 6334-25-4.

What it is

Tetrakis(2-hydroxyethyl)adipamide (CAS 6334-25-4) is a crystalline beta-hydroxyalkylamide with four hydroxyl groups. It is the standard TGIC-free curative for outdoor-durable polyester powder coatings.

How it works

On baking, its hydroxyl groups react with the carboxyl groups of a polyester resin (esterification) to crosslink into a hard, weatherable film; it gives excellent exterior durability and avoids TGIC. It releases water on cure, so degassing/film thickness are managed.

Applications

It is used as the crosslinker in TGIC-free exterior-durable polyester powder coatings (architectural, outdoor). The TGIC route is triglycidyl isocyanurate.

Forms, grades and handling

Supplied as a fine crystalline powder in bags and drums. Properties are typical reference values; the Certificate of Analysis (CoA) for the lot you buy governs. Isocyanates are moisture-sensitive and require respiratory/skin precautions; handle per the current Safety Data Sheet (SDS). Each lot ships with CoA, TDS and SDS.

Bulk supply and RFQ

RawSource sources Tetrakis direct from producers in bulk, with CoA, TDS and SDS per lot. Tell us your binder system, cure schedule and the performance you need, and we will quote the right grade. See the epoxy curing agents guide.

Typical Properties

Typical reference values, not a specification; the Certificate of Analysis (CoA) for the lot governs.

Property Typical Value
Chemical / class beta-Hydroxyalkylamide crosslinker
Function TGIC-free powder-coating crosslinker
CAS Number 6334-25-4
Molecular Formula C14H28N2O6
Handling Refer to the current SDS

Regulatory & registration requirements

  • TSCA (US):
  • REACH (EU):
  • EC number: 405-370-0

TSCA Inventory flag PMN: a commenced PMN (premanufacture notice) substance (EPA flag legend).

Source: EPA TSCA Inventory (July 2025 release) · ECHA CHEM — retrieved 2026-07-12

Frequently Asked Questions

What is tetrakis(2-hydroxyethyl)adipamide used for?

Tetrakis(2-hydroxyethyl)adipamide (Primid-type HAA, CAS 6334-25-4) is the TGIC-free beta-hydroxyalkylamide crosslinker for carboxyl-polyester powder coatings, giving weatherable exterior-durable films.

How is bulk tetrakis(2-hydroxyethyl)adipamide supplied and quoted?

RawSource supplies tetrakis(2-hydroxyethyl)adipamide in bulk with CoA, TDS and SDS per lot. Pricing is quote-based on grade and volume; submit an RFQ with your binder system and cure schedule.

What is the REACH and TSCA regulatory status of N,N,N',N'-Tetrakis(2-Hydroxyethyl)adipamide?

N,N,N',N'-Tetrakis(2-Hydroxyethyl)adipamide (CAS 6334-25-4) is subject to U.S. TSCA Inventory requirements; supplying it into the EU requires valid REACH registration ((EC) No 1907/2006). RawSource cannot verify a third-party supplier's registrations — buyers should require documented TSCA and REACH compliance for their jurisdiction and volume (EC 405-370-0).

Disclaimer. Information on this page — including properties, identifiers, hazard, transport (DOT/UN) and tariff (HS) classifications, and applications — is provided for general reference and is compiled from authoritative public sources (e.g. PubChem/ECHA, 49 CFR 172.101, the Harmonized Tariff Schedule). Values are typical and are not a guaranteed specification; the Certificate of Analysis (CoA) for the lot purchased governs. Products are sold for industrial and professional use only. Nothing here is a medical, health, or efficacy claim or advice. Always consult the current Safety Data Sheet (SDS) before handling, storage, transport or disposal, and confirm regulatory status, classification and suitability for your application and jurisdiction. Hazard, transport and tariff classifications must be verified for your specific shipment. RawSource makes no warranty, express or implied, and assumes no liability for use of this information. Trademarks. Third-party trademarks and brand names are the property of their respective owners; any reference is nominative — used only to identify a comparable product — and does not imply affiliation with, sponsorship by, or endorsement by the trademark owner.