Methyltrioctylammonium chloride (TOMAC, CAS 5137-55-3) is a quaternary ammonium chloride salt. It functions as a phase-transfer catalyst and is used in liquid chromatography for separations. It is also permitted as an inert ingredient in non-food pesticide products.
Regulatory & registration requirements
- TSCA (US):
- REACH (EU):
- EC number: 225-896-2
Source: EPA TSCA Inventory (July 2025 release) · ECHA CHEM — retrieved 2026-07-12
Solutions Using This Product
Process-solution guides on this site that specify this chemistry:
Frequently Asked Questions
What does Aliquat® 336 do?
Aliquat 336 (methyltrioctylammonium chloride, TOMAC, CAS 5137-55-3) is a quaternary ammonium chloride salt that acts as a phase-transfer catalyst, ferrying ionic reagents into the organic phase to drive two-phase reactions. It is also used in liquid chromatography separations and is permitted as an inert ingredient in non-food pesticide products.
What is methyltrioctylammonium chloride used for?
It is used as a phase-transfer catalyst in organic synthesis, as a stationary/mobile-phase modifier in high-performance liquid chromatography separations including tRNA, and as an extractant carrier in liquid-liquid metal extraction. It also serves as an inert formulation additive in non-food pesticide products.
Is Aliquat 336 the same as Adogen® 464 or tricaprylylmethylammonium chloride?
These are closely related quaternary ammonium chloride surfactants with C8 (octyl/caprylyl) alkyl chains and overlapping CAS coverage, and are often used interchangeably as phase-transfer catalysts. Exact chain-length distribution and assay vary by source, so specify your required purity and confirm identity against the CoA.
What is the molecular formula of methyltrioctylammonium chloride?
Its representative formula is C25H54ClN (CAS 5137-55-3). It is a cationic surfactant supplied as a viscous liquid; request the SDS and CoA for assay and physical-property data.
How is Aliquat 336 supplied in bulk?
RawSource supplies cationic surfactants such as methyltrioctylammonium chloride in bulk industrial packaging including drums and totes/IBCs for synthesis and separations users. Pricing varies with grade and volume, so submit a bulk quote with your target quantity and packaging; a CoA and SDS accompany each shipment.
What is the REACH and TSCA regulatory status of Methyltrioctylammonium Chloride (TOMAC, Trioctylmethylammonium Chloride)?
Methyltrioctylammonium Chloride (TOMAC, Trioctylmethylammonium Chloride) (CAS 5137-55-3) is subject to U.S. TSCA Inventory requirements; supplying it into the EU requires valid REACH registration ((EC) No 1907/2006). RawSource cannot verify a third-party supplier's registrations — buyers should require documented TSCA and REACH compliance for their jurisdiction and volume (EC 225-896-2).
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Adogen® (Evonik (historical Sherex/Witco/Goldschmidt)), Aliquat® (BASF (historical General Mills/Henkel/Cognis)) are trademarks of their respective owners. RawSource is not affiliated with, endorsed by, or sponsored by these companies; names are referenced for comparison and compatibility identification only.