CHLOROFORM- ▸ Fluorocarbon feedstock: Raw material for HCFC-22 and fluoropolymers
- ▸ Extraction solvent: Solvent for fats, oils, resins, and waxes
- ▸ Laboratory reagent: Solvent and reagent in chemical synthesis
A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.
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Transport classification per the UN Model Regulations / 49 CFR 172.101 Hazardous Materials Table. Confirm against the grade-specific SDS (Section 14) before shipping.
⚠ WARNING: This product can expose you to Chloroform, which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
Chloroform (CAS 67-66-3), or trichloromethane, is a chlorinated solvent and chemical intermediate. Its principal use is as a feedstock in the manufacture of chlorodifluoromethane (HCFC-22) and downstream fluoropolymers. It also serves as an extraction solvent for fats, oils, resins, and waxes and as a laboratory reagent.
Regulatory & registration requirements
- TSCA (US):
- REACH (EU):
- EC number: 200-663-8
Source: EPA TSCA Inventory (July 2025 release) · ECHA CHEM — retrieved 2026-07-12
Regulatory restriction status
Chloroform (Trichloromethane) (CAS 67-66-3) appears on the regulatory list(s) below. This is public regulatory information about the substance — not a statement about any specific supplier’s material, and not a safety claim. Confirm the current status for your jurisdiction and intended use.
- California Proposition 65: listed for cancer and reproductive toxicity, listed 1 Oct 1987. A California Proposition 65 warning applies (see the warning above).
- REACH Restriction (Annex XVII), entry 32: specific EU uses/conditions of the substance are restricted.
Sources: ECHA Candidate List / Annex XIV / Annex XVII (echa.europa.eu); U.S. EPA TSCA; UN Stockholm Convention / EU POPs Regulation; California OEHHA Proposition 65 list. Retrieved 2026-07-13.
Frequently Asked Questions
What is chloroform used for?
Chloroform (CAS 67-66-3) is primarily a chemical feedstock for the manufacture of chlorodifluoromethane (HCFC-22) and downstream fluoropolymers. It is also used as an extraction solvent for fats, oils, resins, and waxes, and as a laboratory reagent and solvent in chemical synthesis.
What is the chemical formula and other name for chloroform?
Chloroform has the formula CHCl3 and the systematic name trichloromethane (CAS 67-66-3). It is a chlorinated aliphatic solvent. RawSource supplies it as an industrial-grade solvent and intermediate.
Is chloroform a good solvent for fats and oils?
Yes. Chloroform is an effective extraction solvent for lipophilic materials including fats, oils, resins, and waxes, which is one of its established industrial and laboratory uses. Solubility behavior and handling parameters are described in the SDS.
How is chloroform classified for shipping?
Chloroform is assigned UN 1888 and is regulated for transport; its HS code is 290313. Packaging and shipping mode follow DOT requirements and the SDS. Contact RawSource to confirm container options for bulk orders.
What is the cost of bulk chloroform?
Bulk chloroform pricing varies with grade, packaging, and volume. RawSource provides quotes for drum, tote, and larger industrial quantities rather than a published price. Send your volume and grade requirements for a current bulk quote and lead time.
What is the REACH and TSCA regulatory status of Chloroform (Trichloromethane)?
Chloroform (Trichloromethane) (CAS 67-66-3) is subject to U.S. TSCA Inventory requirements; supplying it into the EU requires valid REACH registration ((EC) No 1907/2006). RawSource cannot verify a third-party supplier's registrations — buyers should require documented TSCA and REACH compliance for their jurisdiction and volume (EC 200-663-8).