- ▸ Precursor to 2,6-difluorobenzamide and benzoylurea insect growth regulators such as diflubenzuron (Agriculture)
- ▸ Fluorinated building block for pharmaceutical actives (Pharmaceuticals, Industrial Manufacturing)
A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.
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2,6-Difluorobenzonitrile is a fluoro-benzonitrile synthesis intermediate — a building block used in the manufacture of agrochemical intermediates, notably as a precursor toward benzoylurea-type actives via 2,6-difluorobenzamide. Identity: CAS 1897-52-5.
What it is
2,6-Difluorobenzonitrile (CAS 1897-52-5, C7H3F2N) is a fluoro-benzonitrile sold as a synthesis intermediate — a defined building block that downstream manufacturers convert into finished products. It is a key building block for benzoylurea agrochemical chemistry.
Role in synthesis
As a nitrile, the cyano group can be hydrolyzed to the corresponding acid or amide, or reduced to a primary amine, while the ring halogens are reactive sites for nucleophilic aromatic substitution. The substitution pattern (isomer) is part of the identity — confirm the CAS to be sure the isomer matches your route, because position isomers react differently and lead to different products.
What it is used to make
It is a building block toward agrochemical intermediates, notably as a precursor toward benzoylurea-type actives via 2,6-difluorobenzamide. RawSource supplies the intermediate; the downstream synthesis, product registration and any application or efficacy are the responsibility of the manufacturer that uses it.
Forms, grades and handling
Supplied to a defined assay with a Certificate of Analysis (CoA) per lot; define the assay and key impurity limits your route needs. Several halo-aromatic intermediates are hazardous and some are regulated — confirm regulatory status and handling for your jurisdiction, and always consult the current Safety Data Sheet (SDS). Typical values are not a guaranteed specification; the CoA governs.
Bulk and custom-quantity supply
RawSource sources 2,6-Difluorobenzonitrile direct from producers in bulk and custom quantities, with CoA, TDS and SDS per lot. Tell us the assay and impurity limits and your sample/pilot/production quantity, and we will quote it and confirm supply continuity. See the full range in the intermediates guide.
Typical Properties
Typical reference values, not a specification; the Certificate of Analysis (CoA) for the lot governs.
| Property | Typical Value |
|---|---|
| Type | Fluoro-benzonitrile |
| End-use class | Agrochemical intermediate (benzoylureas) |
| CAS Number | 1897-52-5 |
| Molecular Formula | C7H3F2N |
| Molecular Weight | 139.10 g/mol |
| Handling | Refer to the current SDS |
Regulatory & registration requirements
- TSCA (US):
- REACH (EU):
- EC number: 217-589-7
Source: EPA TSCA Inventory (July 2025 release) · ECHA CHEM — retrieved 2026-07-12
Frequently Asked Questions
What is 2,6-difluorobenzonitrile used to make?
2,6-Difluorobenzonitrile (CAS 1897-52-5) is a synthesis intermediate used toward benzoylurea-type agrochemical actives, typically via hydrolysis to 2,6-difluorobenzamide. RawSource supplies the intermediate only.
Can RawSource supply 2,6-difluorobenzonitrile in bulk or custom quantities?
Yes — RawSource supplies 2,6-difluorobenzonitrile in bulk and custom (sample/pilot/production) quantities with CoA, TDS and SDS per lot. Tell us the assay, impurity limits and quantity, and we will quote it and confirm supply.
What is the REACH and TSCA regulatory status of 2,6-Difluorobenzonitrile?
2,6-Difluorobenzonitrile (CAS 1897-52-5) is subject to U.S. TSCA Inventory requirements; supplying it into the EU requires valid REACH registration ((EC) No 1907/2006). RawSource cannot verify a third-party supplier's registrations — buyers should require documented TSCA and REACH compliance for their jurisdiction and volume (EC 217-589-7).