Polymers & Resins Available — Bulk Only

Methylene Diphenyl Diisocyanate (MDI)

MDI
CAS 101-68-8 · Formula C15H10N2O2 · MW 250.25 g/mol

The aromatic diisocyanate that drives rigid polyurethane foam, TPU, and reaction-injection-molding chemistry. Pure and polymeric MDI grades also feed reaction-injection-molded parts, thermoplastic polyurethane elastomers, adhesives and binders, two-component coatings, and spandex fibers.

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HS Code
2929.10
At a Glance
Material Family
Polymers & Resins
Record Type
Pure compound
Primary Role
Crosslinking / Curing · Synthesis Intermediate
Functional Roles
METHYLENE DIPHENYL DIISOCYANATE
NOT REPORTED
Applications & Use Cases
  • Rigid PU foam: Primary isocyanate for rigid and semi-rigid polyurethane foams.
  • TPU and RIM: Pure MDI for thermoplastic elastomers and reaction-injection molding.
  • Adhesives and binders: Industrial polyurethane adhesives and foundry/wood binders.
  • Coatings: Two-component polyurethane coating systems.
  • Spandex fibers: Used in spandex (elastane) production.
Physical Properties
Physical Description
Diphenylmethane-4,4-diisocyanate is a light yellow colored solid. It is not soluble in water. It may be toxic by ingestion, inhalation, or skin absorption. If in a solution it may or may not burn depending on the nature of the material and/or the solvent. It is used to make plastics
Appearance
White to light yellow flakes
Odor
Odorless
Boiling Point
381 to 199 °C at 5 mmHg
Melting Point
37 °C
Flash Point
218 °C
Solubility
Soluble in acetone, benzene, kerosene, and nitrobenzene
Density
1.2 at 20 °C
Vapor Density
Relative vapor density (air = 1): 8.6
Vapor Pressure
Vapor pressure at 20 °C: negligible
Autoignition Temperature
240 °C
Odor Threshold
Odor Threshold Low: 0.39
Refractive Index
Index of refraction: 1.5906 at 50 °C/D
Safety & Handling
Full SDS available on request

A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.

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HS / Tariff Classification
Harmonized System (HS) Code — 6-digit international heading
2929 . 10
Chapter 29
Organic chemicals
Heading 29.29
Internationally harmonized (WCO HS)
Subheading 2929.10
6-digit international code — national tariff line adds further digits
Chemical Identity
CAS Number
101-68-8
Molecular Formula
C15H10N2O2
Molecular Weight
250.25 g/mol
IUPAC Name
1-isocyanato-4-[(4-isocyanatophenyl)methyl]benzene
INCI Name
METHYLENE DIPHENYL DIISOCYANATE
PubChem CID
InChI Key
UPMLOUAZCHDJJD-UHFFFAOYSA-N
Synonyms & Trade Names
4,4'-Diphenylmethane diisocyanate Diphenylmethane diisocyanate Bis(4-isocyanatophenyl)methane 4,4'-Methylenebis(phenyl isocyanate) Isonate Desmodur 44 p,p'-Diphenylmethane diisocyanate 1,1'-Methylenebis(4-isocyanatobenzene) Methylbisphenyl isocyanate 4,4'-Methylenediphenyl diisocyanate 4,4'-Diisocyanatodiphenylmethane Methylene bisphenyl isocyanate diphenylmethane-4,4'-diisocyanate Caradate 30 Nacconate 300 Diphenylmethyl diisocyanate Bis(p-isocyanatophenyl)methane Isonate 125M Bis(1,4-isocyanatophenyl)methane Methylenebis(4-phenyl isocyanate)
Full Description

Methylene diphenyl diisocyanate (CAS 101-68-8) is an aromatic diisocyanate used chiefly to produce rigid and semi-rigid polyurethane foams. Pure and polymeric MDI grades also feed reaction-injection-molded parts, thermoplastic polyurethane elastomers, adhesives and binders, two-component coatings, and spandex fibers. Supplied as a bulk isocyanate for polyurethane manufacture.

Frequently Asked Questions

What is methylene diphenyl diisocyanate used for?

MDI (CAS 101-68-8) is an aromatic diisocyanate used chiefly to produce rigid and semi-rigid polyurethane foams. Pure and polymeric MDI grades also feed reaction-injection-molded (RIM) parts, thermoplastic polyurethane (TPU) elastomers, adhesives and binders, two-component coatings, and spandex fibers. RawSource supplies it as a bulk isocyanate for polyurethane manufacture.

What is the difference between pure MDI and polymeric MDI?

Pure (monomeric) MDI is used where defined functionality is needed, such as TPU elastomers, RIM parts, and spandex. Polymeric MDI (PMDI) is a higher-functionality mixture used mainly for rigid and semi-rigid foams and binders. RawSource can supply both grades – specify your application for the correct one.

Is MDI flammable?

MDI is not classified as a flammable liquid; it is a reactive aromatic isocyanate that reacts with water and active-hydrogen compounds. It must be kept dry and sealed to prevent reaction and CO2 generation; consult the SDS for full GHS classification and handling.

How is MDI shipped and what CAS/HS codes apply?

MDI ships as UN 2206 (diphenylmethane-4,4'-diisocyanate). CAS 101-68-8; HS code 2929.10 (isocyanates). RawSource supplies it in drums, totes, and bulk with a CoA and SDS per shipment.

What is the cost of bulk MDI?

Bulk MDI pricing depends on grade (pure vs polymeric), volume, packaging, and freight. Request a bulk quote from RawSource with your target quantity and delivery location for current pricing and lead time.

Disclaimer. Information on this page — including properties, identifiers, hazard, transport (DOT/UN) and tariff (HS) classifications, and applications — is provided for general reference and is compiled from authoritative public sources (e.g. PubChem/ECHA, 49 CFR 172.101, the Harmonized Tariff Schedule). Values are typical and are not a guaranteed specification; the Certificate of Analysis (CoA) for the lot purchased governs. Products are sold for industrial and professional use only. Nothing here is a medical, health, or efficacy claim or advice. Always consult the current Safety Data Sheet (SDS) before handling, storage, transport or disposal, and confirm regulatory status, classification and suitability for your application and jurisdiction. Hazard, transport and tariff classifications must be verified for your specific shipment. RawSource makes no warranty, express or implied, and assumes no liability for use of this information. Trademarks. Third-party trademarks and brand names are the property of their respective owners; any reference is nominative — used only to identify a comparable product — and does not imply affiliation with, sponsorship by, or endorsement by the trademark owner.