Amines & Amides Available — Bulk Only

N,N,N’,N’-Tetramethyl-1,3-propanediamine (TMPDA)

CAS 110-95-2 · Formula C7H18N2 · MW 130.23 g/mol

A liquid tertiary diamine catalyst that accelerates urethane and water-isocyanate reactions for tuning cure and rise in polyurethane foam and CASE.

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CAS Number
110-95-2
Formula
C7H18N2
Molecular Weight
130.23 g/mol
Material Family
Amines & Amides
At a Glance
Material Family
Amines & Amides
Primary Role
Crosslinking / Curing
Functional Roles
Applications & Use Cases
  • Bifunctional tertiary-amine catalyst for polyurethane foam and elastomer systems
  • Promotes both blow and gel reactions depending on formulation
  • Used as a co-catalyst to tune reactivity profile
Safety & Handling
Full SDS available on request

A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.

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Chemical Identity
CAS Number
110-95-2
Molecular Formula
C7H18N2
Molecular Weight
130.23 g/mol
IUPAC Name
N,N,N',N'-tetramethylpropane-1,3-diamine
PubChem CID
InChI Key
DMQSHEKGGUOYJS-UHFFFAOYSA-N
XLogP
0.7
Full Description

Tetramethyl-1,3-propanediamine (TMPDA) is a tertiary diamine catalyst for polyurethane — a blow-leaning general catalyst used to tune the reaction profile in foam and CASE. Identity: CAS 110-95-2.

What it is

TMPDA (CAS 110-95-2) is a liquid permethylated 1,3-diamine. Its two tertiary-amine sites give a useful blow/general catalytic activity.

How it catalyzes

It accelerates the urethane and water-isocyanate reactions, leaning toward blow/general activity; it is used to fine-tune cure and rise in combination with other catalysts.

Applications

TMPDA is used in polyurethane foam and CASE to adjust the catalytic balance, with gelling and blowing co-catalysts. Compare TMHDA.

Forms, grades and handling

TMPDA is supplied as a clear liquid in drums, IBCs and bulk. Properties are typical reference values; the Certificate of Analysis (CoA) for the lot you buy governs. Amine catalysts are typically corrosive and have a strong odor — handle per the current Safety Data Sheet (SDS). Each lot ships with CoA, TDS and SDS.

Bulk supply and RFQ

RawSource sources N,N,N’,N’-Tetramethyl-1,3-propanediamine direct from producers in bulk, with CoA, TDS and SDS per lot. Tell us your system (flexible/rigid foam, CASE), the reaction balance you need (gel vs blow), and any low-emission requirement, and we will quote the right catalyst or blend. See the full range and gel/blow selection logic in the polyurethane catalysts guide.

Typical Properties

Typical reference values, not a specification; the Certificate of Analysis (CoA) for the lot governs.

Property Typical Value
Chemical / class Polyurethane catalyst (tertiary diamine)
Catalyst action Blowing / general
CAS Number 110-95-2
Molecular Formula C7H18N2
Molecular Weight 130.23 g/mol
Handling Refer to the current SDS

Regulatory & registration requirements

  • TSCA (US):
  • REACH (EU):
  • EC number: 203-818-8

Source: EPA TSCA Inventory (July 2025 release) · ECHA CHEM — retrieved 2026-07-12

Frequently Asked Questions

What is tetramethyl-1,3-propanediamine (TMPDA) used for?

TMPDA (CAS 110-95-2) is a tertiary diamine catalyst for polyurethane foam and CASE, used to tune the reaction balance (blow/general), in combination with other catalysts.

How is bulk TMPDA supplied and quoted?

RawSource supplies TMPDA in bulk with CoA, TDS and SDS per lot. Pricing is quote-based on grade and volume; submit an RFQ with your PU system and the gel/blow balance you need.

What is the REACH and TSCA regulatory status of N,N,N',N'-Tetramethyl-1,3-propanediamine (TMPDA)?

N,N,N',N'-Tetramethyl-1,3-propanediamine (TMPDA) (CAS 110-95-2) is subject to U.S. TSCA Inventory requirements; supplying it into the EU requires valid REACH registration ((EC) No 1907/2006). RawSource cannot verify a third-party supplier's registrations — buyers should require documented TSCA and REACH compliance for their jurisdiction and volume (EC 203-818-8).

Disclaimer. Information on this page — including properties, identifiers, hazard, transport (DOT/UN) and tariff (HS) classifications, and applications — is provided for general reference and is compiled from authoritative public sources (e.g. PubChem/ECHA, 49 CFR 172.101, the Harmonized Tariff Schedule). Values are typical and are not a guaranteed specification; the Certificate of Analysis (CoA) for the lot purchased governs. Products are sold for industrial and professional use only. Nothing here is a medical, health, or efficacy claim or advice. Always consult the current Safety Data Sheet (SDS) before handling, storage, transport or disposal, and confirm regulatory status, classification and suitability for your application and jurisdiction. Hazard, transport and tariff classifications must be verified for your specific shipment. RawSource makes no warranty, express or implied, and assumes no liability for use of this information. Trademarks. Third-party trademarks and brand names are the property of their respective owners; any reference is nominative — used only to identify a comparable product — and does not imply affiliation with, sponsorship by, or endorsement by the trademark owner.