METHYLENE DIPHENYL DIISOCYANATE- ▸ Rigid PU foam: Primary isocyanate for rigid and semi-rigid polyurethane foams.
- ▸ TPU and RIM: Pure MDI for thermoplastic elastomers and reaction-injection molding.
- ▸ Adhesives and binders: Industrial polyurethane adhesives and foundry/wood binders.
- ▸ Coatings: Two-component polyurethane coating systems.
- ▸ Spandex fibers: Used in spandex (elastane) production.
A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.
Request SDS →Methylene diphenyl diisocyanate (CAS 101-68-8) is an aromatic diisocyanate used chiefly to produce rigid and semi-rigid polyurethane foams. Pure and polymeric MDI grades also feed reaction-injection-molded parts, thermoplastic polyurethane elastomers, adhesives and binders, two-component coatings, and spandex fibers. Supplied as a bulk isocyanate for polyurethane manufacture.
Regulatory & registration requirements
- TSCA (US):
- REACH (EU):
- EC number: 202-966-0
Source: EPA TSCA Inventory (July 2025 release) · ECHA CHEM — retrieved 2026-07-12
Solutions Using This Product
Process-solution guides on this site that specify this chemistry:
- Polyurethane Polyols (Polyether & Polyester) (Industrial Manufacturing)
- Epoxy & Polyurethane Raw Materials (Industrial Manufacturing)
Frequently Asked Questions
What is methylene diphenyl diisocyanate used for?
MDI (CAS 101-68-8) is an aromatic diisocyanate used chiefly to produce rigid and semi-rigid polyurethane foams. Pure and polymeric MDI grades also feed reaction-injection-molded (RIM) parts, thermoplastic polyurethane (TPU) elastomers, adhesives and binders, two-component coatings, and spandex fibers. RawSource supplies it as a bulk isocyanate for polyurethane manufacture.
What is the difference between pure MDI and polymeric MDI?
Pure (monomeric) MDI is used where defined functionality is needed, such as TPU elastomers, RIM parts, and spandex. Polymeric MDI (PMDI) is a higher-functionality mixture used mainly for rigid and semi-rigid foams and binders. RawSource can supply both grades – specify your application for the correct one.
Is MDI flammable?
MDI is not classified as a flammable liquid; it is a reactive aromatic isocyanate that reacts with water and active-hydrogen compounds. It must be kept dry and sealed to prevent reaction and CO2 generation; consult the SDS for full GHS classification and handling.
How is MDI shipped and what CAS/HS codes apply?
MDI ships as UN 2206 (diphenylmethane-4,4'-diisocyanate). CAS 101-68-8; HS code 2929.10 (isocyanates). RawSource supplies it in drums, totes, and bulk with a CoA and SDS per shipment.
What is the cost of bulk MDI?
Bulk MDI pricing depends on grade (pure vs polymeric), volume, packaging, and freight. Request a bulk quote from RawSource with your target quantity and delivery location for current pricing and lead time.
What is the REACH and TSCA regulatory status of Methylene Diphenyl Diisocyanate (MDI)?
Methylene Diphenyl Diisocyanate (MDI) (CAS 101-68-8) is subject to U.S. TSCA Inventory requirements; supplying it into the EU requires valid REACH registration ((EC) No 1907/2006). RawSource cannot verify a third-party supplier's registrations — buyers should require documented TSCA and REACH compliance for their jurisdiction and volume (EC 202-966-0).