CIS-RETINOIC ACIDA grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.
Request SDS →⚠ WARNING: This product can expose you to Isotretinoin, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
Isotretinoin (CAS 4759-48-2) is a retinoid active used in prescription pharmaceuticals for severe acne. RawSource supplies it as a bulk raw material to pharmaceutical manufacturers, not for consumer or therapeutic use.
Regulatory & registration requirements
- TSCA (US):
- REACH (EU): Not determined from public registry
- EC number: 225-296-0
Source: EPA TSCA Inventory (July 2025 release) · ECHA CHEM — retrieved 2026-07-12
Regulatory restriction status
Isotretinoin (CAS 4759-48-2) appears on the regulatory list(s) below. This is public regulatory information about the substance — not a statement about any specific supplier’s material, and not a safety claim. Confirm the current status for your jurisdiction and intended use.
- California Proposition 65: listed for reproductive toxicity, listed 1 Jul 1987. A California Proposition 65 warning applies (see the warning above).
Sources: ECHA Candidate List / Annex XIV / Annex XVII (echa.europa.eu); U.S. EPA TSCA; UN Stockholm Convention / EU POPs Regulation; California OEHHA Proposition 65 list. Retrieved 2026-07-13.