Solvents - Aliphatic Available — Bulk Only

Isohexadecane (Cosmetic Grade)

CAS 4390-04-9 · Formula C16H34 · MW 226.44 g/mol

A branched-chain saturated hydrocarbon supplied as a light emollient oil-phase component. Under the INCI name isohexadecane it is used in personal-care formulations as an emollient and spreading agent.

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CAS Number
4390-04-9
Formula
C16H34
Molecular Weight
226.44 g/mol
Material Family
Solvents - Aliphatic

What is isohexadecane and what is it used for?

Isohexadecane (CAS 4390-04-9) is a branched-chain saturated hydrocarbon supplied as a light emollient oil-phase component. In personal care it is used as a dry-feel emollient, a pigment-wetting and dispersion aid for color cosmetics, a cleansing solvent for long-wear makeup and sunscreen, and a spreading aid in sun care.

At a Glance
Material Family
Solvents - Aliphatic
Record Type
Pure compound
Primary Role
Solvency · Conditioning
Functional Roles
Applications & Use Cases
  • Light emollient: dry, non-greasy after-feel in skin care emulsions
  • Pigment carrier: wetting and dispersion for color cosmetics and long-wear
  • Cleansing solvent: dissolves long-wear makeup and sunscreen in cleansing oils
  • Sun care spreading aid: even film and water-resistance support
  • Oil-phase carrier: vehicle for oil-soluble actives, fragrance, and pigment pastes
Safety & Handling
Full SDS available on request

A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.

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Chemical Identity
CAS Number
4390-04-9
Molecular Formula
C16H34
Molecular Weight
226.44 g/mol
IUPAC Name
2,2,4,4,6,8,8-heptamethylnonane
PubChem CID
InChI Key
VCLJODPNBNEBKW-UHFFFAOYSA-N
Synonyms & Trade Names
Nonane, 2,2,4,4,6,8,8-heptamethyl- (+-)-2,2,4,4,6,8,8-Heptamethylnonane isocetane 2,2,4,4,6,8,8-heptamethyl-nonane Cyprane 2,4,4,6,8,8-Heptamethylnonane Nonane,2,4,4,6,8,8-heptamethyl- 2,2,4,4,6,8,8-?Heptamethylnonane NONANE, 2,2,4,4,6,8,8-HEP-TAMETHYL InChI=1/C16H34/c1-13(10-14(2,3)4)11-16(8,9)12-15(5,6)7/h13H,10-12H2,1-9H
Full Description

Isohexadecane is a branched, fully saturated C16 hydrocarbon emollient (INCI: isohexadecane; commonly the heptamethylnonane structure, CAS 4390-04-9, also registered under the broader isohexadecane CAS 60908-77-2). Because every carbon sits in a branched, saturated chain with no double bonds, it behaves very differently from a plant oil or an ester. It is light and dry on skin, leaves almost no greasy residue, and resists oxidation, which is the same chemistry that keeps it nearly odorless and color-stable over long shelf lives. Formulators reach for it when they want slip and a clean after-feel without the heaviness, tackiness, or rancidity risk of unsaturated oils.

Why branched and saturated matters

The performance comes straight from the structure. Branching keeps the molecule from packing tightly, so it spreads thin and feels light rather than dense like a straight-chain wax or a triglyceride. Full saturation (no C=C bonds) means little for oxygen to attack, so isohexadecane does not go rancid, stays low in odor, and holds color through heat and time. That oxidative stability is the practical edge over many natural emollient oils in formulas that must survive long distribution cycles or warm climates. The trade-off is honest: as a non-polar hydrocarbon it carries lipophilic actives and pigments well but does little to solubilize polar or water-soluble materials, so formulators pair it with a co-solvent or ester when polarity is needed.

Applications by sector

Skin care

In lotions, creams, and serums isohexadecane works as a light emollient and spreading aid. It thins the oil phase, improves glide on application, and dries down to a soft, non-greasy finish — useful in “fast-absorbing” or “non-oily” positioned products where a heavier emollient would feel occlusive. It is frequently used to take the tack out of formulas built on richer butters and esters.

Color cosmetics

This is one of its strongest roles. As a non-polar carrier it wets and disperses pigments evenly, which supports clean color payoff and reduces streaking in foundations, concealers, eyeshadows, and lip products. Its low volatility relative to isododecane and its good spreadability help long-wear and transfer-resistant systems lay down smoothly and blend without dragging. In stick and balm formats it contributes effortless glide.

Sun care

In sunscreens isohexadecane improves the spreadability of the oil phase, helping organic UV filters and dispersed inorganic filters lay down as an even, continuous film that supports uniform coverage. Its hydrophobic character supports water-resistant systems, and it cuts the heavy, greasy feel that high-SPF oil loads can leave. Any water-resistance or SPF performance is established by the finished formula and its own testing, not by a single raw material.

Cleansing oils, makeup removers, and micellar systems

As a light hydrocarbon solvent, isohexadecane dissolves long-wear makeup, sunscreen films, and sebum, making it a workhorse in cleansing oils, balms, biphasic eye-makeup removers, and the oil phase of some micellar systems. It lifts oil-soluble soil and rinses or wipes clean without the dragging feel of heavier oils.

Carrier and solvent

Across categories it serves as a diluent and vehicle for oil-soluble actives, fragrances, and pigment pastes, and as a viscosity-thinning component in the oil phase. Its low odor adds little of its own scent, which helps when a clean or precisely engineered fragrance profile matters.

Forms and grade

RawSource sources cosmetic-grade isohexadecane suitable for personal-care manufacturing, with identity and INCI conformity confirmed lot by lot. Exact purity, typical-value specifications, and INCI documentation are provided on the Certificate of Analysis (CoA) for the lot supplied; we do not publish fixed specification numbers here because they are lot- and source-dependent. If your formulation requires a specific isomer profile, volatility band, or documentation set, specify it on your inquiry and we will source to match.

Handling

Isohexadecane is a combustible hydrocarbon liquid. Storage, handling, and personal protection are governed by the current Safety Data Sheet (SDS) for the lot supplied, which we provide with each shipment. Confirm classification, compatibility, and suitability for your process and jurisdiction before use.

Bulk sourcing from RawSource

RawSource sources isohexadecane in bulk for personal-care manufacturers and contract formulators, in drums, IBC totes, and tanker quantities depending on volume and ship-to. We operate on an RFQ basis: send your target quantity, packaging, and destination, and we return a current quote with a CoA and SDS for the lot. Request a bulk quote.

Frequently Asked Questions

Is isohexadecane a silicone?

No. Isohexadecane is a branched, saturated aliphatic hydrocarbon — purely carbon and hydrogen — not a silicone. Silicones are siloxane polymers built on a silicon-oxygen backbone. Isohexadecane is sometimes chosen as a hydrocarbon alternative to volatile silicones where a light, dry skin-feel is wanted without a siloxane.

What is isohexadecane used for?

It is a light emollient and spreading agent in skin care, a pigment-wetting carrier in color cosmetics, a spreadability aid in sun care, and a solvent in cleansing oils and makeup removers. Across categories it also serves as an oil-phase carrier and diluent for oil-soluble actives, fragrances, and pigments. Formulators value its light, dry after-feel and oxidative stability.

Why choose a branched hydrocarbon over a plant oil or ester?

The branched, fully saturated structure spreads thin for a light, non-greasy feel and resists oxidation, so it stays low in odor and color-stable over long shelf lives rather than going rancid like many unsaturated natural oils. The trade-off is polarity: as a non-polar hydrocarbon it carries lipophilic materials well but does little for water-soluble or highly polar ingredients, which formulators address with a co-solvent or ester.

Can isohexadecane be used in hair products?

Yes. As a branched hydrocarbon emollient and spreading agent it is used in the oil phase of hair-care formulations for slip and a light conditioning feel without weighing hair down. Validate loading and compatibility in your own system.

How is isohexadecane supplied in bulk, and how do I get pricing?

RawSource sources cosmetic-grade isohexadecane in bulk industrial packaging (drums, IBC totes, and tankers) on an RFQ basis. Pricing is volume-, packaging-, and destination-dependent. Send your target quantity and ship-to for a current quote; a CoA and SDS are provided with each lot.

Disclaimer. Information on this page — including properties, identifiers, hazard, transport (DOT/UN) and tariff (HS) classifications, and applications — is provided for general reference and is compiled from authoritative public sources (e.g. PubChem/ECHA, 49 CFR 172.101, the Harmonized Tariff Schedule). Values are typical and are not a guaranteed specification; the Certificate of Analysis (CoA) for the lot purchased governs. Products are sold for industrial and professional use only. Nothing here is a medical, health, or efficacy claim or advice. Always consult the current Safety Data Sheet (SDS) before handling, storage, transport or disposal, and confirm regulatory status, classification and suitability for your application and jurisdiction. Hazard, transport and tariff classifications must be verified for your specific shipment. RawSource makes no warranty, express or implied, and assumes no liability for use of this information. Trademarks. Third-party trademarks and brand names are the property of their respective owners; any reference is nominative — used only to identify a comparable product — and does not imply affiliation with, sponsorship by, or endorsement by the trademark owner.