Solvents - Oxygenated Available — Bulk Only

Dimethylformamide (DMF)

DMF
CAS 68-12-2 · Formula C3H7NO · MW 73.09 g/mol

A high-boiling polar aprotic solvent used in acrylic fiber spinning, polymer film processing, synthetic leather manufacture, and as a reaction medium.

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UN Number
UN 2265
Hazard Class
Class 3
HS Code
2924.19
At a Glance
Material Family
Solvents - Oxygenated
Record Type
Pure compound
Primary Role
Solvency · Synthesis Intermediate
Solubility
Miscible with ethanol, ethyl ether, acetone, benzene; slightly soluble in ligroin
Functional Roles
Applications & Use Cases
  • Acrylic fiber spinning: Solvent for acrylic and other synthetic fibers.
  • Synthetic leather: Solvent for polyurethane coating systems.
  • Coatings and films: Processes polymer films and surface coatings.
  • Reaction medium: Solvent and crystallization medium in synthesis.
Physical Properties
Physical Description
N,n-dimethylformamide appears as a water-white liquid with a faint fishy odor. Flash point 58 °C. Slightly less dense than water. Vapors heavier than air. Toxic by inhalation or skin absorption. May irritate eyes
Appearance
Colorless to very slightly yellow liquid
Odor
Faint, amine-like odor
Boiling Point
BP: 76 °C at 39 mm Hg; 25 °C at 3.7 mm Hg
Melting Point
-61 °C
Flash Point
67 °C (open cup); 58 °C (Closed cup)
Solubility
Miscible with ethanol, ethyl ether, acetone, benzene; slightly soluble in ligroin
Density
0.95 at 20 °C
Vapor Density
2.51
Vapor Pressure
3.7 mmHg at 25 °C; 2.7 mmHg at 20 °C
LogP
log Kow = -1.01
Henry's Law Constant
Henry's Law constant = 7.39X10-8 atm-cu m/mole at 25 °C
Autoignition Temperature
445 °C
Viscosity
0.85 mm²/s at 25 °C
Corrosivity
Pure dimethylformamide is essentially noncorrosive to metals. However, copper, tin and their alloys should be avoided
Heat Of Combustion
1921 kJ/mole at 25 °C
Heat of Vaporization
47.6 kJ/mole at 25 °C
pH
pH = 6.7 (0.5 molar solution in water)
Surface Tension
36.42 dyne/cm at 25 °C
Ionization Potential
9.12 eV
Polymerization
Methylene diisocyanate polymerized violently on contact with dimethyl formamide
Odor Threshold
300 mg/cu m (odor low) 300 mg/cu m (odor high)
Refractive Index
Index of refraction: 1.42083 at 25 °C/D
Dissociation Constants
pKa = -0.30 (conjugate acid)
Safety & Handling
Full SDS available on request

A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.

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DOT / UN Transport Classification
DOT hazard class 3 placard
UN / DOT NumberUN 2265
Hazard Class / DivisionClass 3
Packing GroupIII
Proper Shipping NameN,N-Dimethylformamide

Transport classification per the UN Model Regulations / 49 CFR 172.101 Hazardous Materials Table. Confirm against the grade-specific SDS (Section 14) before shipping.

HS / Tariff Classification
Harmonized System (HS) Code — 6-digit international heading
2924 . 19
Chapter 29
Organic chemicals
Heading 29.24
Internationally harmonized (WCO HS)
Subheading 2924.19
6-digit international code — national tariff line adds further digits
Chemical Identity
CAS Number
68-12-2
Molecular Formula
C3H7NO
Molecular Weight
73.09 g/mol
IUPAC Name
N,N-dimethylformamide
PubChem CID
InChI Key
ZMXDDKWLCZADIW-UHFFFAOYSA-N
Synonyms & Trade Names
N,N-DIMETHYLFORMAMIDE Dimethylformamide Dimethyl formamide N-Formyldimethylamine Formamide, N,N-dimethyl- Dimethylformamid DMFA N,N-Dimethyl formamide Formyldimethylamine Dimetilformamide Dwumetyloformamid Dimetylformamidu DMF (amide) NCI-C60913 N,N Dimethylformamide Dimethylamid kyseliny mravenci N,N-Dimetilformamida U-4224 Formic acid, amide, N,N-dimethyl-
Full Description

⚠ WARNING: This product can expose you to Dimethylformamide, which is known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov.

Dimethylformamide (CAS 68-12-2) is a high-boiling polar aprotic solvent. It is used to spin acrylic fibers, to process polymer films and surface coatings, in synthetic leather and wire-enamel manufacture, and as a reaction and crystallization medium.

Regulatory & registration requirements

  • TSCA (US):
  • REACH (EU):
  • EC number: 200-679-5

Source: EPA TSCA Inventory (July 2025 release) · ECHA CHEM — retrieved 2026-07-12

Regulatory restriction status

Dimethylformamide (DMF) (CAS 68-12-2) appears on the regulatory list(s) below. This is public regulatory information about the substance — not a statement about any specific supplier’s material, and not a safety claim. Confirm the current status for your jurisdiction and intended use.

  • California Proposition 65: listed for cancer, listed 27 Oct 2017. A California Proposition 65 warning applies (see the warning above).
  • REACH Restriction (Annex XVII), entry 76: specific EU uses/conditions of the substance are restricted.
  • REACH SVHC Candidate List (EU): listed 19 Dec 2012 on the basis of toxic for reproduction (Art. 57(c)). SVHC status triggers EU supplier-communication and notification duties above 0.1% w/w; it is not, by itself, a ban on sale.

Sources: ECHA Candidate List / Annex XIV / Annex XVII (echa.europa.eu); U.S. EPA TSCA; UN Stockholm Convention / EU POPs Regulation; California OEHHA Proposition 65 list. Retrieved 2026-07-13.

Solutions Using This Product

Process-solution guides on this site that specify this chemistry:

Frequently Asked Questions

What is dimethylformamide (DMF) used for?

DMF is a high-boiling polar aprotic solvent. Industrial uses include spinning acrylic and other synthetic fibers, processing polymer films and surface coatings, manufacturing synthetic leather (as a solvent for polyurethane coating systems) and wire enamels, and serving as a reaction and crystallization medium in chemical synthesis.

What is dimethylformamide made from?

DMF (CAS 68-12-2, C3H7NO) is the N,N-dimethyl amide of formic acid. It is produced industrially by reacting dimethylamine with carbon monoxide or with methyl formate. RawSource supplies it as a finished solvent in bulk; CoA and SDS accompany each shipment.

Is DMF the same as dimethyl sulfoxide (DMSO)?

No. DMF (CAS 68-12-2) is an amide solvent, C3H7NO; DMSO is a sulfoxide, C2H6OS, CAS 67-68-5. Both are polar aprotic solvents but differ in chemistry, boiling point, and application. Confirm the CAS on the CoA to ensure you receive the correct material.

How is DMF shipped and classified for transport?

DMF ships under UN 2265 (N,N-dimethylformamide). The HS classification is 2924.19 (acyclic amides and derivatives). DOT/IMDG documentation and the SDS are provided with each bulk order; request the current SDS for full handling and transport detail.

What is the cost of bulk dimethylformamide?

Bulk DMF pricing depends on volume, packaging (drums, totes, or bulk), grade, and destination. We do not list a fixed price; submit a bulk RFQ with your required quantity and ship-to location for a current quote, CoA, and SDS.

What is the REACH and TSCA regulatory status of Dimethylformamide (DMF)?

Dimethylformamide (DMF) (CAS 68-12-2) is subject to U.S. TSCA Inventory requirements; supplying it into the EU requires valid REACH registration ((EC) No 1907/2006). RawSource cannot verify a third-party supplier's registrations — buyers should require documented TSCA and REACH compliance for their jurisdiction and volume (EC 200-679-5).

Disclaimer. Information on this page — including properties, identifiers, hazard, transport (DOT/UN) and tariff (HS) classifications, and applications — is provided for general reference and is compiled from authoritative public sources (e.g. PubChem/ECHA, 49 CFR 172.101, the Harmonized Tariff Schedule). Values are typical and are not a guaranteed specification; the Certificate of Analysis (CoA) for the lot purchased governs. Products are sold for industrial and professional use only. Nothing here is a medical, health, or efficacy claim or advice. Always consult the current Safety Data Sheet (SDS) before handling, storage, transport or disposal, and confirm regulatory status, classification and suitability for your application and jurisdiction. Hazard, transport and tariff classifications must be verified for your specific shipment. RawSource makes no warranty, express or implied, and assumes no liability for use of this information. Trademarks. Third-party trademarks and brand names are the property of their respective owners; any reference is nominative — used only to identify a comparable product — and does not imply affiliation with, sponsorship by, or endorsement by the trademark owner.