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Dimethyl Isosorbide (DMI)

DMI
CAS 5306-85-4 · Formula C8H14O4 · MW 174.19 g/mol

A biobased dianhydrohexitol diether that solubilizes stubborn actives where conventional solvents fall short. It is used as a high-polarity solvent, solubilizer, and stabilizing agent, including in personal-care formulations.

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HS Code
2932.99
At a Glance
Material Family
Specialty Additives
Record Type
Pure compound
Primary Role
Solvency · Viscosity Modification
Functional Roles
Solvency Viscosity Modification Wetting
INCI Name
DIMETHYL ISOSORBIDE
CosIng Functions
SOLVENTVISCOSITY CONTROLLING
Industries Served
Beauty & Personal Care
Applications & Use Cases
  • ▸ Solvent: High-polarity solvent for poorly soluble actives.
  • ▸ Solubilizer: Solubilizing agent in formulated products.
  • ▸ Stabilizer: Stabilizing agent in formulations.
  • ▸ Personal care: Carrier solvent in personal-care products.
Physical Properties
Physical Description
Liquid
Safety & Handling
Full SDS available on request

A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.

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HS / Tariff Classification
Harmonized System (HS) Code — 6-digit international heading
2932 . 99
Chapter 29
Organic chemicals
Heading 29.32
Internationally harmonized (WCO HS)
Subheading 2932.99
6-digit international code — national tariff line adds further digits
Chemical Identity
CAS Number
5306-85-4
Molecular Formula
C8H14O4
Molecular Weight
174.19 g/mol
IUPAC Name
(3S,3aR,6R,6aR)-3,6-dimethoxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan
INCI Name
DIMETHYL ISOSORBIDE
PubChem CID
62990
InChI Key
MEJYDZQQVZJMPP-ULAWRXDQSA-N
Synonyms & Trade Names
Isosorbide dimethyl ether Dimethyl isosorbide 2,5-Dimethylisosorbide 1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol D-Glucitol, 1,4:3,6-dianhydro-2,5-di-O-methyl- 2,5-O-dimethylisosorbide Arlasolve DMI (3R,3aR,6S,6aR)-3,6-Dimethoxyhexahydrofuro[3,2-b]furan (3S,3aR,6R,6aR)-3,6-dimethoxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan 2,5-Di-O-methyl-1,4:3,6-dianhydro-D-glucitol (3R,3aR,6S,6aR)-3,6-dimethoxy-hexahydrofuro[3,2-b]furan dimethyl isosorbide ether
Full Description

Dimethyl isosorbide (CAS 5306-85-4), or DMI, is the dimethyl diether of isosorbide, a bicyclic dianhydrohexitol. It is used as a high-polarity solvent, solubilizer, and stabilizing agent, including in personal-care formulations.

Frequently Asked Questions

What is dimethyl isosorbide (DMI) used for?

Dimethyl isosorbide (DMI, CAS 5306-85-4) is the dimethyl diether of isosorbide. It is used as a high-polarity solvent, solubilizer, and stabilizing agent, including as a carrier solvent for poorly soluble actives in personal-care and formulated products.

Is dimethyl isosorbide a naturally derived solvent?

DMI is the dimethyl diether of isosorbide, a bicyclic dianhydrohexitol that derives from sorbitol/sugar feedstocks; the finished material is a synthetically produced high-polarity solvent. Confirm any bio-based or naturality claims against the supplier specification for your grade.

What is the CAS number and formula of dimethyl isosorbide?

Dimethyl isosorbide has CAS number 5306-85-4 and molecular formula C8H14O4. It is a specialty solvent/solubilizer. Each bulk lot ships with a CoA referencing this CAS.

What HS code does dimethyl isosorbide ship under?

DMI is classified under HS 2932.99 (heterocyclic compounds with oxygen hetero-atoms only: other). Verify the destination tariff line and documentation with your customs broker.

How is bulk dimethyl isosorbide packaged and priced?

RawSource supplies DMI in drums, totes, and IBCs to personal-care and specialty-formulation manufacturers, with CoA and SDS per lot. Pricing is quote-based on volume and packaging; request a current bulk quote rather than a list price.

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Disclaimer. Information on this page — including properties, identifiers, hazard, transport (DOT/UN) and tariff (HS) classifications, and applications — is provided for general reference and is compiled from authoritative public sources (e.g. PubChem/ECHA, 49 CFR 172.101, the Harmonized Tariff Schedule). Values are typical and are not a guaranteed specification; the Certificate of Analysis (CoA) for the lot purchased governs. Products are sold for industrial and professional use only. Nothing here is a medical, health, or efficacy claim or advice. Always consult the current Safety Data Sheet (SDS) before handling, storage, transport or disposal, and confirm regulatory status, classification and suitability for your application and jurisdiction. Hazard, transport and tariff classifications must be verified for your specific shipment. RawSource makes no warranty, express or implied, and assumes no liability for use of this information. Trademarks. Third-party trademarks and brand names are the property of their respective owners; any reference is nominative — used only to identify a comparable product — and does not imply affiliation with, sponsorship by, or endorsement by the trademark owner.
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