Specialty Additives Available — Bulk Only

Croscarmellose Sodium (Cross-Linked Carboxymethylcellulose Sodium)

CAS 74811-65-7

A cross-linked cellulose-gum superdisintegrant used to drive rapid tablet break-up. Used as a superdisintegrant excipient in pharmaceutical and nutraceutical tablets and capsules, where it swells on wetting to break dosage forms apart.

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HS Code
3912.31
At a Glance
Material Family
Specialty Additives
Record Type
Pure compound
Primary Role
Thickening / Rheology
Functional Roles
Industries Served
Applications & Use Cases
  • Tablet disintegrant: Superdisintegrant for rapid tablet and capsule break-up
  • Nutraceuticals: Disintegrant in supplement dosage forms
  • Pharmaceutical excipient: Formulation aid in solid oral dosage manufacture
Safety & Handling
Full SDS available on request

A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.

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HS / Tariff Classification
Harmonized System (HS) Code — 6-digit international heading
3912 . 31
Chapter 39
Plastics and articles thereof
Heading 39.12
Internationally harmonized (WCO HS)
Subheading 3912.31
6-digit international code — national tariff line adds further digits
Chemical Identity
CAS Number
74811-65-7
Full Description

Croscarmellose sodium (CAS 74811-65-7), the internally cross-linked sodium salt of carboxymethylcellulose. Used as a superdisintegrant excipient in pharmaceutical and nutraceutical tablets and capsules, where it swells on wetting to break dosage forms apart. Supplied as a white powder.

Frequently Asked Questions

What is croscarmellose sodium used for in supplements and tablets?

Croscarmellose sodium (CAS 74811-65-7) is used as a superdisintegrant excipient in pharmaceutical and nutraceutical tablets and capsules. On contact with water it swells rapidly, breaking the dosage form apart to aid dissolution. It functions as a formulation aid in solid oral dosage manufacture.

Is croscarmellose a natural ingredient?

Croscarmellose sodium is the internally cross-linked sodium salt of carboxymethylcellulose, a cellulose derivative. The base cellulose is plant-derived, but the material is chemically modified (carboxymethylated and cross-linked), so it is a processed cellulose derivative rather than an unmodified natural substance.

Is croscarmellose sodium water soluble?

Croscarmellose sodium is not freely water soluble; the internal cross-linking causes it to swell and absorb water rather than dissolve, which is exactly what drives its disintegrant action. Refer to the product SDS and technical data sheet for handling and dispersion details.

What grade and packaging does RawSource supply croscarmellose sodium in?

RawSource supplies croscarmellose sodium as a white powder for excipient use, classified under HS code 3912.31 (carboxymethylcellulose and its salts). Grade documentation, packaging, and lot size are confirmed per order, with a CoA and SDS provided. Request a bulk quote with your required specification and quantity.

What is the cost of bulk croscarmellose sodium?

Bulk pricing varies by grade, packaging, order volume, and destination, so it is quoted per order rather than published. Submit a bulk RFQ with your quantity and spec and RawSource will return current pricing.

Disclaimer. Information on this page — including properties, identifiers, hazard, transport (DOT/UN) and tariff (HS) classifications, and applications — is provided for general reference and is compiled from authoritative public sources (e.g. PubChem/ECHA, 49 CFR 172.101, the Harmonized Tariff Schedule). Values are typical and are not a guaranteed specification; the Certificate of Analysis (CoA) for the lot purchased governs. Products are sold for industrial and professional use only. Nothing here is a medical, health, or efficacy claim or advice. Always consult the current Safety Data Sheet (SDS) before handling, storage, transport or disposal, and confirm regulatory status, classification and suitability for your application and jurisdiction. Hazard, transport and tariff classifications must be verified for your specific shipment. RawSource makes no warranty, express or implied, and assumes no liability for use of this information. Trademarks. Third-party trademarks and brand names are the property of their respective owners; any reference is nominative — used only to identify a comparable product — and does not imply affiliation with, sponsorship by, or endorsement by the trademark owner.