Amines & Amides Available — Bulk Only

Sodium Polyglutamate (Sodium PGA)

CAS 25513-46-6 · Formula C5H8NNaO4 · MW 169.11 g/mol

Water-soluble polyamino-acid biopolymer for humectancy and film formation in cosmetic systems. It is used as a humectant and film-forming agent in cosmetic formulations and as a chelating agent.

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CAS Number
25513-46-6
Formula
C5H8NNaO4
Molecular Weight
169.11 g/mol
Material Family
Amines & Amides
At a Glance
Material Family
Amines & Amides
Record Type
Pure compound
Primary Role
Moisture Control · Film Formation
Solubility
Freely soluble in water; practically insoluble in ethanol or ether
Functional Roles
POLYGLUTAMIC ACID
SKIN CONDITIONING
Applications & Use Cases
  • Humectant: Water-binding agent in cosmetic formulations.
  • Film former: Forms a flexible film in cosmetic formulations.
  • Chelating agent: Sequesters metal ions.
Physical Properties
Solubility
Freely soluble in water; practically insoluble in ethanol or ether
pH
Between 6,7 and 7,2 (5 % solution)
Safety & Handling
Full SDS available on request

A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.

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Chemical Identity
CAS Number
25513-46-6
Molecular Formula
C5H8NNaO4
Molecular Weight
169.11 g/mol
IUPAC Name
sodium (2S)-2-amino-5-hydroxy-5-oxopentanoate
INCI Name
POLYGLUTAMIC ACID
PubChem CID
InChI Key
LPUQAYUQRXPFSQ-DFWYDOINSA-M
Synonyms & Trade Names
PGA-Na Poly-γ-Glutamic Acid Sodium Salt Sodium Poly(γ-Glutamic Acid) Sodium γ-PGA Sodium glutamate Glutamate, Sodium Sodium L-glutamate Monosodium L-glutamate l-Monosodium glutamate L-(+)Sodium glutamate L-Glutamic acid Monosodium salt Sodium (S)-2-amino-4-carboxybutanoate Sodium polyglutamate L-Glutamic Acid Monosodium sodium;(2S)-2-amino-5-hydroxy-5-oxopentanoate Accent sodium (2S)-2-amino-4-carboxybutanoate MSG Sodium glutamate (VAN) L-GLUTAMIC ACID SODIUM
Full Description

Sodium polyglutamate (sodium PGA, the sodium salt of poly-gamma-glutamic acid; INCI Sodium Polyglutamate; CAS 25513-46-6) is a high-molecular-weight, fermentation-derived polymer of glutamic acid. It is an exceptionally strong water-binding humectant and a film former — it holds many times its weight in water and lays down a smooth, flexible film, which makes it a moisture-feel and texture agent in skin and hair care.

What is sodium polyglutamate?

It is the sodium salt of poly-gamma-glutamic acid (γ-PGA), a natural biopolymer produced by fermentation. Its many carboxylate groups bind and hold water strongly, giving high humectancy with a smooth, non-tacky feel, and the polymer forms a light, flexible film on drying. It is water-soluble and anionic.

Applications by sector

Skin care. A strong water-binding humectant and film former that improves moisture feel, smoothness and a soft after-finish in serums, creams and masks. Hair care. A conditioning, film-forming and water-binding polymer that adds smoothness and manageability. Texture. A thickening and sensory modifier. These describe water-binding and formulation behavior, not skin-health or hydration claims about the user.

Forms and grades

Supplied as a powder or solution; confirm form, molecular-weight grade and active content on the RFQ. Related humectants: glycereth-26, glycerin.

Handling and documentation

Each lot ships with a Certificate of Analysis (CoA); request the Safety Data Sheet (SDS) for handling data.

Bulk supply and RFQ

RawSource supplies sodium polyglutamate in bulk to personal-care formulators, with CoA and SDS per lot. Submit an RFQ with your form, grade and target quantity.

Typical Properties

Typical reference values, not a specification; the Certificate of Analysis (CoA) for the lot governs.

Property Typical Value
INCI Name Sodium Polyglutamate
CAS Number 25513-46-6
Chemical type Fermentation-derived sodium salt of poly-gamma-glutamic acid (anionic biopolymer)
Appearance White powder or aqueous solution
Solubility Water-soluble
Function Humectant (strong water-binding); film former; texture/conditioning
Handling Refer to the current SDS

Frequently Asked Questions

What is sodium polyglutamate used for?

Sodium polyglutamate (sodium PGA, CAS 25513-46-6) is a strong water-binding humectant and film former used in skin and hair care to improve moisture feel, smoothness and a soft finish.

How does sodium polyglutamate compare to hyaluronic acid or glycerin?

Like other polymeric humectants it binds and holds water strongly while forming a light film; it is chosen for high water-binding with a smooth, non-tacky feel. Choose by feel, film and cost; these are formulation properties, not health claims.

Is sodium polyglutamate natural-derived?

It is produced by fermentation (a bio-derived polymer). We describe its origin and formulation behavior rather than making an unqualified “natural” marketing claim.

What is the CAS of sodium polyglutamate?

It is CAS 25513-46-6. As a biopolymer it is supplied by molecular-weight grade; the CoA documents each lot.

How is bulk sodium polyglutamate supplied and quoted?

RawSource supplies it as a powder or solution in bulk with CoA and SDS per lot. Pricing is quote-based on grade and volume; submit an RFQ with your target quantity.

Disclaimer. Information on this page — including chemical properties, identifiers, hazard, transport (DOT/UN) and tariff (HS) classifications, and applications — is provided for general reference and is compiled from authoritative public sources (e.g. PubChem). Values are typical and are not a guaranteed specification; the Certificate of Analysis (CoA) for the lot you purchase governs. Products are sold for industrial and professional use only. Nothing here is a medical, health, or efficacy claim, or advice. Always consult the current Safety Data Sheet (SDS) before handling, storage, transport or disposal, and confirm regulatory status, classification and suitability for your application and jurisdiction. Hazard, transport and tariff classifications must be verified for your specific shipment. RawSource makes no warranty, express or implied, and assumes no liability for use of this information.

Disclaimer. Information on this page — including properties, identifiers, hazard, transport (DOT/UN) and tariff (HS) classifications, and applications — is provided for general reference and is compiled from authoritative public sources (e.g. PubChem/ECHA, 49 CFR 172.101, the Harmonized Tariff Schedule). Values are typical and are not a guaranteed specification; the Certificate of Analysis (CoA) for the lot purchased governs. Products are sold for industrial and professional use only. Nothing here is a medical, health, or efficacy claim or advice. Always consult the current Safety Data Sheet (SDS) before handling, storage, transport or disposal, and confirm regulatory status, classification and suitability for your application and jurisdiction. Hazard, transport and tariff classifications must be verified for your specific shipment. RawSource makes no warranty, express or implied, and assumes no liability for use of this information. Trademarks. Third-party trademarks and brand names are the property of their respective owners; any reference is nominative — used only to identify a comparable product — and does not imply affiliation with, sponsorship by, or endorsement by the trademark owner.