Specialty Additives Available — Bulk Only

Sodium Acetylated Hyaluronate

CAS 158254-23-0

An acetyl-modified hyaluronate that binds water while clinging to skin better than its unmodified counterpart. It is used as a humectant and skin-conditioning ingredient in cosmetic formulations, where the acetyl modification raises lipophilicity and substantivity relative to standard sodium hyaluronate.

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HS Code
3913.90
At a Glance
Material Family
Specialty Additives
Record Type
UVCB
Primary Role
Moisture Control · Conditioning
Solubility
Soluble in water forming a viscous solution; insoluble in ethanol and most organic solvents (typical)
Functional Roles
SODIUM ACETYLATED HYALURONATE
HUMECTANT
Industries Served
Applications & Use Cases
  • Humectant: Water-binding humectant for skin-care emulsions and serums.
  • Skin conditioning: Film-forming, smoothing skin-conditioning agent.
  • Substantive moisturization: Acetylated form for improved skin adhesion versus sodium hyaluronate.
Physical Properties
Appearance
White to off-white powder or granules (typical)
Physical State
Solid (typical)
Solubility
Soluble in water forming a viscous solution; insoluble in ethanol and most organic solvents (typical)
pH 1% Aqueous
5.0-8.5 (1% aqueous solution, typical)
Molecular Weight Range
Variable polysaccharide; grade-dependent (typical)
Safety & Handling
Full SDS available on request

A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.

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HS / Tariff Classification
Harmonized System (HS) Code — 6-digit international heading
3913 . 90
Chapter 39
Plastics and articles thereof
Heading 39.13
Internationally harmonized (WCO HS)
Subheading 3913.90
6-digit international code — national tariff line adds further digits
Chemical Identity
CAS Number
158254-23-0
INCI Name
SODIUM ACETYLATED HYALURONATE
Synonyms & Trade Names
Acetylated Sodium Hyaluronate Sodium Acetyl Hyaluronate Acetyl Hyaluronic Acid Sodium Salt Acetylated Hyaluronic Acid Sodium Salt Sodium Acetylhyaluronate Hyaluronic Acid Acetate Sodium Salt
Full Description

Sodium acetylated hyaluronate (CAS 158254-23-0) is the sodium salt of acetylated hyaluronic acid, a modified glycosaminoglycan biopolymer. It is used as a humectant and skin-conditioning ingredient in cosmetic formulations, where the acetyl modification raises lipophilicity and substantivity relative to standard sodium hyaluronate.

Frequently Asked Questions

What is sodium acetylated hyaluronate?

Sodium acetylated hyaluronate (CAS 158254-23-0) is the sodium salt of acetylated hyaluronic acid, a modified glycosaminoglycan biopolymer. It is supplied as a cosmetic raw material used as a humectant and skin-conditioning ingredient.

Is sodium acetylated hyaluronate the same as hyaluronic acid?

No. It is a chemically modified, acetylated derivative of the hyaluronic acid biopolymer, supplied as its sodium salt. The acetyl modification raises lipophilicity and substantivity relative to standard sodium hyaluronate, so it is a distinct material with different formulation behavior.

How does sodium acetylated hyaluronate compare to sodium hyaluronate?

Both derive from the hyaluronic acid biopolymer, but the acetylated form carries acetyl groups that increase lipophilicity and skin adhesion (substantivity) versus standard sodium hyaluronate. This can affect how it is dispersed and how it performs as a film-forming humectant in a formulation.

Is sodium acetylated hyaluronate water soluble?

As a sodium salt it is water-dispersible/soluble, though the acetyl modification raises lipophilicity compared with sodium hyaluronate. Confirm hydration method and use level against the product technical data when formulating serums and emulsions.

How is sodium acetylated hyaluronate supplied and quoted in bulk?

It is supplied as a cosmetic raw material (powder) under HS 3913.90, modified natural polymers. Pricing is volume- and market-dependent; request a bulk quote with your target quantity and specification. A CoA and SDS are provided.

Disclaimer. Information on this page — including properties, identifiers, hazard, transport (DOT/UN) and tariff (HS) classifications, and applications — is provided for general reference and is compiled from authoritative public sources (e.g. PubChem/ECHA, 49 CFR 172.101, the Harmonized Tariff Schedule). Values are typical and are not a guaranteed specification; the Certificate of Analysis (CoA) for the lot purchased governs. Products are sold for industrial and professional use only. Nothing here is a medical, health, or efficacy claim or advice. Always consult the current Safety Data Sheet (SDS) before handling, storage, transport or disposal, and confirm regulatory status, classification and suitability for your application and jurisdiction. Hazard, transport and tariff classifications must be verified for your specific shipment. RawSource makes no warranty, express or implied, and assumes no liability for use of this information. Trademarks. Third-party trademarks and brand names are the property of their respective owners; any reference is nominative — used only to identify a comparable product — and does not imply affiliation with, sponsorship by, or endorsement by the trademark owner.