Amines & Amides Available — Bulk Only

Acetyl Hexapeptide-8 (Acetyl Hexapeptide-3)

CAS 616204-22-9

A synthetic peptide active supplied as a water-based solution for cosmetic skin-care formulators. It is a CIR-listed cosmetic ingredient used as a peptide (skin-conditioning) active in skin-care formulations.

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CAS Number
616204-22-9
Material Family
Amines & Amides
At a Glance
Material Family
Amines & Amides
Record Type
Pure compound
Primary Role
Conditioning · Moisture Control
Functional Roles
ACETYL HEXAPEPTIDE-8
HUMECTANTSKIN CONDITIONING
Applications & Use Cases
  • Cosmetic skin care: peptide active for facial skin-care formulations
  • Skin conditioning: skin-conditioning ingredient in serums and creams
  • Leave-on formulations: water-soluble peptide solution for leave-on products
Safety & Handling
Full SDS available on request

A grade-specific Safety Data Sheet (SDS) — with the complete hazard classification, handling precautions, and transport information — is supplied with every shipment and available on request. Confirm all safety and regulatory details against the SDS for your specific grade.

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Chemical Identity
CAS Number
616204-22-9
INCI Name
ACETYL HEXAPEPTIDE-8
Synonyms & Trade Names
Acetyl hexapeptide-3 Acetyl Hexapeptide-8 Argireline NP Hexapeptide 3 Acetyl hexapeptide 3 Acetyl-glu-glu-met-gln-arg-arg-amide ACETYL HEXAPEPTIDE-8 [INCI] ARGIRELINE Botulinoid Acetyl Hexapeptide-8 (Powder) Acetyl Hexapeptide-8 (Liquid) argireline
Full Description

Acetyl hexapeptide-8 (CAS 616204-22-9), a synthetic acetylated hexapeptide supplied as an aqueous solution (Aqua). It is a CIR-listed cosmetic ingredient used as a peptide (skin-conditioning) active in skin-care formulations.

Frequently Asked Questions

What is acetyl hexapeptide-8 used for in skin care?

Acetyl hexapeptide-8 (CAS 616204-22-9) is a synthetic acetylated hexapeptide, supplied here as an aqueous (Aqua) solution. It is a CIR-listed cosmetic ingredient used as a peptide skin-conditioning active in serums, creams, and leave-on facial formulations.

Is acetyl hexapeptide-8 synthetic or natural?

It is synthetic. Acetyl hexapeptide-8 is a manufactured acetylated hexapeptide (formula C35H62N14O11S), supplied as a water-soluble peptide solution for cosmetic formulation.

Is acetyl hexapeptide-8 the same as Argireline?

Argireline is a well-known trade name associated with acetyl hexapeptide-8. The underlying cosmetic ingredient is the same acetyl hexapeptide-8 (CAS 616204-22-9); branded versions may differ in concentration and the aqueous carrier system.

What is the active concentration of this acetyl hexapeptide-8 solution?

This product is supplied as Aqua, Acetyl Hexapeptide-8 — an aqueous solution rather than neat peptide. The active peptide concentration is stated on the CoA; specify your target use level so we can confirm the appropriate grade.

How is acetyl hexapeptide-8 solution supplied to formulators?

We supply the water-soluble acetyl hexapeptide-8 solution in bulk to cosmetic manufacturers. Request a quote with your target volume and required active concentration, and we will provide pricing, CoA, and SDS.

Disclaimer. Information on this page — including properties, identifiers, hazard, transport (DOT/UN) and tariff (HS) classifications, and applications — is provided for general reference and is compiled from authoritative public sources (e.g. PubChem/ECHA, 49 CFR 172.101, the Harmonized Tariff Schedule). Values are typical and are not a guaranteed specification; the Certificate of Analysis (CoA) for the lot purchased governs. Products are sold for industrial and professional use only. Nothing here is a medical, health, or efficacy claim or advice. Always consult the current Safety Data Sheet (SDS) before handling, storage, transport or disposal, and confirm regulatory status, classification and suitability for your application and jurisdiction. Hazard, transport and tariff classifications must be verified for your specific shipment. RawSource makes no warranty, express or implied, and assumes no liability for use of this information. Trademarks. Third-party trademarks and brand names are the property of their respective owners; any reference is nominative — used only to identify a comparable product — and does not imply affiliation with, sponsorship by, or endorsement by the trademark owner.